Julolidine hydrobromide

Base Information

• Chemical Name: Julolidine hydrobromide
• CAS No.: 83646-41-7
• Molecular Formula: C12H15 N . Br H
• Molecular Weight: 254.17
• European Community (EC) Number: 625-925-2
• DSSTox Substance ID: DTXSID10482656
• Mol file: 83646-41-7.mol

Synonyms:Julolidine hydrobromide;83646-41-7;1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8-triene;hydrobromide;1,2,3,5,6,7-Hexahydropyrido[3,2,1-ij]quinoline hydrobromide;2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinoline hydrobromide;Julolidine hydrobromide, 97%;SCHEMBL8863742;DTXSID10482656;AKOS015897201;AC-19443;CS-0456087

Chemical Property of Julolidine hydrobromide

Chemical Property:

• Vapor Pressure: 3.13E-05mmHg at 25°C
• Melting Point: 239-242 °C(lit.)
• Boiling Point: 347.2°C at 760 mmHg
• Flash Point: 163.8°C
• PSA: 3.24000
• LogP: 3.40850
• Sensitive.: Hygroscopic
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 253.04661
• Heavy Atom Count: 14
• Complexity: 172

Purity/Quality:

98%Min ^*data from raw suppliers

Julolidine hydrobromide 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T
• Statements: 14-23/24/25-34
• Safety Statements: 26-27-36/37/39-45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=C3C(=CC=C2)CCCN3C1.Br
• Uses: Julolidine hydrobromide may be used in the synthesis of [4-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-ylazo)-phenyl]-methanol azodye.

Technology Process of Julolidine hydrobromide

There total 1 articles about Julolidine hydrobromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline hydrobromide (83646-41-7)

Guidance literature:

Reference yield: 55.0%

4-aminobenzenemethanol (623-04-1) + 1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline hydrobromide (83646-41-7) → [4-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-ylazo)phenyl]methanol (1346458-34-1)

Guidance literature:

4-aminobenzenemethanol; With hydrogenchloride; sodium nitrite; In water; at -0.16 ℃; for 0.5h;

1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline hydrobromide; With sodium acetate; for 1h; pH=4;

DOI:10.1016/j.dyepig.2011.09.001

Reference yield:

1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline hydrobromide (83646-41-7) → 9-julolidinecarboxaldehyde (33985-71-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0.75 h / 0 °C

1.2: 0 - 40 °C

2.1: sodium hydroxide / water; methanol / pH Ca_. 8 - 9

With sodium hydroxide; trichlorophosphate; In methanol; water; 1.1: |Vilsmeier Reaction / 1.2: |Vilsmeier Reaction;

DOI:10.1515/znb-2016-0009

Downstream raw materials:

[4-(2,3,6,7-tetrahydro-1H,5H-pyrido[3,2,1-ij]quinolin-9-ylazo)phenyl]methanol

9-julolidinecarboxaldehyde