N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride

Base Information

• Chemical Name: N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride
• CAS No.: 1099778-02-5
• Molecular Formula: C₁₄H₂₃NO₅*ClH
• Molecular Weight: 321.801
• Mol file: 1099778-02-5.mol

Synonyms:N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride

Chemical Property of N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride

There total 3 articles about N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3,4,5-trimethoxy-benzaldehyde (86-81-7) + 2,2-dimethoxyethylamine (22483-09-6) → N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride (1099778-02-5) + (3,4,5-trimethoxyphenyl)methanol (3840-31-1)

Guidance literature:

With chloroform; 10% Pd/C; hydrogen; In methanol; at 20 ℃; for 5h; under 760.051 Torr; chemoselective reaction;

DOI:10.1016/j.tet.2008.09.072

Reference yield: 97.0%

3,4,5-trimethoxy-benzaldehyde (86-81-7) + 2,2-dimethoxyethylamine (22483-09-6) → N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride (1099778-02-5)

Guidance literature:

With chloroform; 10% Pd/C; hydrogen; In methanol; at 20 ℃; for 5h; under 1551.49 Torr; chemoselective reaction;

DOI:10.1016/j.tet.2008.09.072

Reference yield: 89.0%

3,4,5-trimethoxy-benzaldehyde (86-81-7) + 2,2-dimethoxyethylamine (22483-09-6) → N-(2,2-dimethoxyethyl)-3,4,5-trimethoxybenzylamine hydrochloride (1099778-02-5) + (3,4,5-trimethoxyphenyl)methanol (3840-31-1) + aminoacetaldehyde dimethyl acetal hydrochloride (56766-81-5)

Guidance literature:

With chloroform; 10% Pd/C; hydrogen; In methanol; at 20 ℃; for 5h; under 760.051 Torr; chemoselective reaction;

DOI:10.1016/j.tet.2008.09.072

upstream raw materials:

3,4,5-trimethoxy-benzaldehyde

2,2-dimethoxyethylamine

Refernces