alanine p-nitroanilide

Base Information

• Chemical Name: alanine p-nitroanilide
• CAS No.: 26432-41-7
• Molecular Formula: C₉H₁₁N₃O₃
• Molecular Weight: 209.205
• Mol file: 26432-41-7.mol

Synonyms:alanine p-nitroanilide

Chemical Property of alanine p-nitroanilide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of alanine p-nitroanilide

There total 5 articles about alanine p-nitroanilide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

t-butoxycarbonyl-L-alanine p-nitroanilide (52815-81-3) → L-alanine-p-nitroanilide (1668-13-9,26017-82-3,26432-41-7,77286-89-6)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2008.07.051

Reference yield:

benzyl (S)-(1-((4-nitrophenyl)amino)-1-oxopropan-2-yl)carbamate (1168-86-1) → L-alanine-p-nitroanilide (1668-13-9,26017-82-3,26432-41-7,77286-89-6)

Guidance literature:

With hydrogen bromide; In acetic acid;

DOI:10.1248/cpb.30.4060

Reference yield:

N-succinyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide (52299-14-6) → L-alanine-p-nitroanilide (1668-13-9,26017-82-3,26432-41-7,77286-89-6) + N-succinyl-Ala-Ala (141509-27-5)

Guidance literature:

With endopeptidase; In various solvent(s); at 25 ℃; for 1h; pH=8.0; apparent rate of hydrolysis;

DOI:10.1248/cpb.34.275

upstream raw materials:

N,N-phthaloyl-DL-alanine-(4-nitro-anilide)

N-succinyl-L-alanyl-L-alanyl-L-alanine 4-nitroanilide

benzyl (S)-(1-((4-nitrophenyl)amino)-1-oxopropan-2-yl)carbamate

t-butoxycarbonyl-L-alanine p-nitroanilide

Downstream raw materials:

[({[(S)-1-(4-Nitro-phenylcarbamoyl)-ethylcarbamoyl]-methyl}-carbamoyl)-methyl]-carbamic acid benzyl ester

((S)-1-{(S)-3-Methyl-1-[(S)-1-(4-nitro-phenylcarbamoyl)-ethylcarbamoyl]-butylcarbamoyl}-ethyl)-carbamic acid benzyl ester

N-acetylleucyl-leucyl-alanine p-nitroanilide

Z-Ala-Ala-Ala-pNA

Refernces

• 1、 Kaneda, Makoto,Yonezawa, Hiroo,Uchikoba, Tetsuya. "Purification and Some Properties of a Protease from the Sarcocarp of Musk Melon Fruit". . p. 2100 - 2102. Retrieved 2007/10/03.
• 2、 Shimamori,Watanabe,Fujimoto. "Specificity of a membrane-bound neutral endopeptidase from rat kidney.". . p. 275 - 280. Retrieved 2007/10/02.