potassium trifluoro(3-methylphenethyl)borate

Base Information

• Chemical Name: potassium trifluoro(3-methylphenethyl)borate
• CAS No.: 1431794-51-2
• Molecular Formula: C₉H₁₁BF₃*K
• Molecular Weight: 226.091
• Mol file: 1431794-51-2.mol

Synonyms:potassium trifluoro(3-methylphenethyl)borate

Chemical Property of potassium trifluoro(3-methylphenethyl)borate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of potassium trifluoro(3-methylphenethyl)borate

There total 3 articles about potassium trifluoro(3-methylphenethyl)borate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane (1431792-81-2) → potassium trifluoro(3-methylphenethyl)borate (1431794-51-2)

Guidance literature:

With potassium hydrogen bifluoride; In water; acetonitrile; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2013.03.056

Reference yield:

3-methylstyrene (100-80-1) → potassium trifluoro(3-methylphenethyl)borate (1431794-51-2)

Guidance literature:

Multi-step reaction with 2 steps

1: bis(1,5-cyclooctadiene)diiridium(I) dichloride; 1,4-di(diphenylphosphino)-butane / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

2: potassium hydrogen bifluoride / water; acetonitrile / 1 h / 20 °C

With bis(1,5-cyclooctadiene)diiridium(I) dichloride; potassium hydrogen bifluoride; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran; water; acetonitrile;

DOI:10.1016/j.bmcl.2013.03.056

Reference yield:

potassium hydrogen difluoride + C9H13BO2 → potassium trifluoro(3-methylphenethyl)borate (1431794-51-2)

Guidance literature:

In methanol; water; for 2h;

DOI:10.1021/acs.orglett.8b02095

upstream raw materials:

3-methylstyrene

4,4,5,5-tetramethyl-2-(3-methylphenethyl)-1,3,2-dioxaborolane

Downstream raw materials:

2-(3-methylphenyl)ethanol

Refernces

• 1、 Yonezawa, Shuji,Yamakawa, Hidekuni,Muto, Chie,Hosono, Motoko,Yamamoto, Takahiko,Hattori, Kazunari,Sakagami, Masahiro,Togame, Hiroko,Tanaka, Yoshikazu,Nakano, Toru,Takemoto, Hiroshi,Arisawa, Mitsuhiro,Shuto, Satoshi. "Conformational restriction approach to BACE1 inhibitors II: SAR study of the isocytosine derivatives fixed with a cis-cyclopropane ring". . p. 2912 - 2915. Retrieved 2013/06/26.