(ethyl)(methyl)(phenyl)phosphine sulfide

Base Information

• Chemical Name: (ethyl)(methyl)(phenyl)phosphine sulfide
• CAS No.: 13639-73-1
• Molecular Formula: C₉H₁₃PS
• Molecular Weight: 184.242
• Mol file: 13639-73-1.mol

Synonyms:(ethyl)(methyl)(phenyl)phosphine sulfide

Chemical Property of (ethyl)(methyl)(phenyl)phosphine sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (ethyl)(methyl)(phenyl)phosphine sulfide

There total 7 articles about (ethyl)(methyl)(phenyl)phosphine sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

dimethylphenylphosphine sulfide (1707-00-2) + methyl iodide (74-88-4) → (ethyl)(methyl)(phenyl)phosphine sulfide (13639-73-1)

Guidance literature:

dimethylphenylphosphine sulfide; With n-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 1h; Inert atmosphere; Schlenk technique;

methyl iodide; In tetrahydrofuran; cyclohexane; at -78 ℃; for 0.5h; Inert atmosphere; Schlenk technique;

DOI:10.1021/acs.joc.7b01767

Reference yield: 45.0%

methylmagnesium bromide (75-16-1) + ethylmagnesium bromide (925-90-6) + cis-2,10-dimethyl-<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole (119841-34-8,127780-84-1) + phenylmagnesium bromide → Diethyl-methyl-phosphin-sulfid (1706-98-5) + (ethyl)(methyl)(phenyl)phosphine sulfide (13639-73-1) + methyldiphenylphosphine sulfide (13639-74-2) + 4-methyl-2-[(5-methyl-2-sulfanylphenyl)phosphanyl]benzenethiol (736137-64-7)

Guidance literature:

ethylmagnesium bromide; cis-2,10-dimethyl-<1,2,3>benzothiadiphospholo<2,3-b><1,2,3>benzothiadiphosphole; phenylmagnesium bromide; In tetrahydrofuran; for 0.0833333h;

methylmagnesium bromide; In tetrahydrofuran;

With sulfur; In tetrahydrofuran;

DOI:10.1021/jo0502145

Reference yield:

meso-1,2-dimethyl-1,2-diphenyldiphosphine disulfide (3619-83-8) → (ethyl)(methyl)(phenyl)phosphine sulfide (13639-73-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Cl₂

2: diethyl ether

With chlorine; In diethyl ether;

DOI:10.1021/jo01285a015

upstream raw materials:

chloromethylphenylphosphine sulfide

ethylmagnesium bromide

C₁₂H₁₉PS

methyl iodide

Downstream raw materials:

ethylmethylphenylphosphine oxide

Refernces

• 1、 Baccolini, Graziano,Boga, Carla,Mazzacurati, Marzia. "Highly atom-economic one-pot formation of three different C-P bonds: General synthesis of acyclic tertiary phosphine sulfides". . p. 4774 - 4777. Retrieved 2007/10/03.