C₁₀H₇F₂IN₂

Base Information

• Chemical Name: C₁₀H₇F₂IN₂
• CAS No.: 1231747-27-5
• Molecular Formula: C₁₀H₇F₂IN₂
• Molecular Weight: 320.08
• Mol file: 1231747-27-5.mol

Synonyms:C₁₀H₇F₂IN₂

Chemical Property of C₁₀H₇F₂IN₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₀H₇F₂IN₂

There total 1 articles about C₁₀H₇F₂IN₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2-(bromomethyl)-1-fluoro-3-iodobenzene (1231747-49-1) + 4-fluoro-1H-pyrazole (35277-02-2) → C10H7F2IN2 (1231747-27-5)

Guidance literature:

With sodium hydride; In tetrahydrofuran; Reflux;

DOI:10.1016/j.tetlet.2010.03.080

Reference yield: 78.0%

C10H7F2IN2 (1231747-27-5) + trimethylsilylacetylene (1066-54-2) → C15H16F2N2Si (1231747-29-7)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; triethylamine; In N,N-dimethyl-formamide;

DOI:10.1016/j.tetlet.2010.03.080

Reference yield:

2-vinyl-1,3-dioxolane (3984-22-3) + C10H7F2IN2 (1231747-27-5) → C15H14F2N2O2

Guidance literature:

With palladium diacetate; triethylamine; tris-(o-tolyl)phosphine; In acetonitrile; at 120 ℃;

DOI:10.1016/j.tetlet.2010.03.080

upstream raw materials:

2-(bromomethyl)-1-fluoro-3-iodobenzene

4-fluoro-1H-pyrazole

Downstream raw materials:

C₁₅H₁₆F₂N₂Si

Refernces