Fmoc-12-Ado-OH

Base Information Edit

Chemical Name:Fmoc-12-Ado-OH
CAS No.:128917-74-8
Molecular Formula:C27H35NO4
Molecular Weight:437.579
Hs Code.:2924299090
DSSTox Substance ID:DTXSID50401149
Wikidata:Q82204203
Mol file:128917-74-8.mol

Synonyms:Fmoc-12-Ado-OH;128917-74-8;12-(9H-fluoren-9-ylmethoxycarbonylamino)dodecanoic Acid;12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoic acid;Dodecanoic acid, 12-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-;12-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)dodecanoic acid;Fmoc-Adod(12)-OH;SCHEMBL178760;n-fmoc-12-aminododecanoic acid;DTXSID50401149;N-(9-FLUORENYLMETHYLOXYCARBONYL)-12-AMINO-DODECANOIC ACID;MFCD00235888;AKOS015909977;DS-6019;BP-28249;CS-0149770;Fmoc-12-Ado-OH, >=98.0% (TLC);FT-0697523;C72173;EN300-650265;Z2044793447;12-(((9H-fluoren-9-yl)methoxy)carbonylamino)dodecanoic acid;12-[[(9H-Fluoren-9-ylmethoxy)carbonyl]amino]dodecanoic acid;Dodecanoicacid,12-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-;3-[([[1-(4-CHLOROPHENYL)ETHYLIDENE]AMINO]OXY)METHYL]BENZOICACID

Suppliers and Price of Fmoc-12-Ado-OH

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Fmoc-12-aminododecanoic acid
2g
$ 333.00

TRC
12-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)dodecanoicAcid
5 g
$ 330.00

Sigma-Aldrich
Fmoc-12-Ado-OH ≥98.0% (TLC)
500mg
$ 124.00

Crysdot
Fmoc-12-Ado-OH 95+%
25g
$ 475.00

Crysdot
Fmoc-12-Ado-OH 95+%
10g
$ 238.00

Crysdot
Fmoc-12-Ado-OH 95+%
100g
$ 1436.00

Chem-Impex
Fmoc-12-aminododecanoicacid,95%(HPLC) 95%(HPLC)
25G
$ 991.20

Chem-Impex
Fmoc-12-aminododecanoicacid,≥95%(HPLC) ≥95%(HPLC)
1G
$ 46.59

Chem-Impex
Fmoc-12-aminododecanoicacid,95%(HPLC) 95%(HPLC)
5G
$ 207.20

Chemenu
Fmoc-12-Ado-OH 95%
25g
$ 449.00

Total 25 raw suppliers

Chemical Property of Fmoc-12-Ado-OH Edit

Chemical Property:

Melting Point:102 °C
Boiling Point:628.8 °C at 760 mmHg
PKA:4.78±0.10(Predicted)
Flash Point:334.1 °C
PSA：75.63000
Density:1.119 g/cm³
LogP:6.90160
Storage Temp.:Store at 0°C
XLogP3:6.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:15
Exact Mass:437.25660860
Heavy Atom Count:32
Complexity:544

Purity/Quality:

98%,99%, ^*data from raw suppliers

Fmoc-12-aminododecanoic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(C3=CC=CC=C32)COC(=O)NCCCCCCCCCCCC(=O)O
Description Fmoc-12-aminododecanoic acid is an alkane chian with terminal Fmoc-protected amine and carboxylic acid groups. The compound can be used as a PROTAC linker in the synthesis of PROTACs. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Technology Process of Fmoc-12-Ado-OH

There total 2 articles about Fmoc-12-Ado-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%