(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione

Base Information Edit

Chemical Name:(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione
CAS No.:446292-07-5
Molecular Formula:C21H21N3O5
Molecular Weight:395.415
Hs Code.:2922498590
European Community (EC) Number:610-200-5
UNII:MKJ6JPP9AB
DSSTox Substance ID:DTXSID10467923
Wikidata:Q72480821
Mol file:446292-07-5.mol

Synonyms:446292-07-5;(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione;2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione;2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-;2-[(2R)-2-hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl]isoindole-1,3-dione;CKFVSMPWXAASIQ-MRXNPFEDSA-N;2-((2R)-2-Hydroxy-3-{[4-(3-oxo-4-morpholinyl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione;MKJ6JPP9AB;4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone;EC 610-200-5;SCHEMBL77318;AMY4159;DTXSID10467923;BCP27211;CS-M0561;MFCD11977664;AKOS016007842;DS-4456;1H-Isoindole-1,3(2H)-dione,2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-;2-((2R)-2-Hydroxy-3-((4-(3-oxo-4-morpholinyl) phenyl)amino)propyl)-1H-isoindole-1,3(2H)-dione;AC-25296;F12082;A854756;(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)-amino)propyl)isoindoline-1,3-dione;(R)-2-(2-hydroxy-3-(4-(3-oxo-morpholino)phenylamino)propyl)isoindoline-1,3-dione;(R)-2-(2-hydroxy-3-(4-(3-oxomorpholino)phenylamino)propyl)isoindoline-1,3-dione;2-{(2R)-2-Hydroxy-3-[4-(3-oxomorpholin-4-yl)anilino]propyl}-1H-isoindole-1,3(2H)-dione;2-{2(R)-Hydroxy-3-[4-(3-oxo-morpholin-4-yl)phenyl amino]-propyl}-isoindole-1,3-dione;(R)-2-(2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione;1H-Isoindole-1,3(2H)-dione, 2-[(2R)-2-hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl];2((2R)-2-Hydroxy-3-{[4-(3-oxo-4-morpholinyl)phenyl]amino}propyl)-1H-iso-indole-1,3(2H)-dione;2-((2R)-2-Hydroxy-3-{ [4-(3-oxo-4-morpholinyl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione;2-((2R)-2-hydroxy-3-{[4-(3-oxo-4-morpholinyl)-phenyl]amino}propyl)-1H-isoindole-1,3(2H)dione;2-((2R)-2-Hydroxy-3-{[4-(3-oxo-4-morpholinyl)phenyl]amino}propyl)-1H-iso-indole-1,3(2H)-dione;2-((2R)-2-Hydroxy-3{[4-(3-oxo-4-morpholinyl)phenyl]amino}propyl)-1H-iso-indole-1,3(2H)-dione;2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]-amino]propyl]-1H-isoindole-1,3(2H)-dione;2-[(2R)-2-hydroxy-3-{[4(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione;2-[(2R)-2-hydroxy-3-{[4-(3-oxo morpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione

Suppliers and Price of (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
50mg
$ 725.00

TRC
4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone
25mg
$ 385.00

SynQuest Laboratories
2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]amino]propyl]-1H-isoindole-1,3(2H)-dione
1 g
$ 192.00

Matrix Scientific
2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]-amino]propyl]-1H-isoindole-1,3(2H)-dione >97%
1g
$ 194.00

Crysdot
(R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione 95+%
10g
$ 110.00

Chemenu
2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]-amino]propyl]-1H-isoindole-1,3(2H)-dione 95%
10g
$ 281.00

Chemenu
2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]-amino]propyl]-1H-isoindole-1,3(2H)-dione 95%
5g
$ 184.00

Chemenu
2-[(2R)-2-Hydroxy-3-[[4-(3-oxo-4-morpholinyl)phenyl]-amino]propyl]-1H-isoindole-1,3(2H)-dione 95%
25g
$ 561.00

Chemcia Scientific
(R)-2-{2-Hydroxy-3-[4-(3-oxo-morpholin-4-yl)-phenylamino]-propyl}-isoindole-1,3-dione 95%
5 G
$ 950.00

Chemcia Scientific
(R)-2-{2-Hydroxy-3-[4-(3-oxo-morpholin-4-yl)-phenylamino]-propyl}-isoindole-1,3-dione 95%
1 G
$ 305.00

Total 131 raw suppliers

Chemical Property of (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:208-211°C
Refractive Index:1.672
Boiling Point:734.905 °C at 760 mmHg
PKA:13.91±0.20(Predicted)
Flash Point:398.256 °C
PSA：99.18000
Density:1.421 g/cm³
LogP:1.19470
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)
Water Solubility.:37mg/L at 20℃
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:395.14812078
Heavy Atom Count:29
Complexity:610

Purity/Quality:

99.5%min ^*data from raw suppliers

4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1COCC(=O)N1C2=CC=C(C=C2)NCC(CN3C(=O)C4=CC=CC=C4C3=O)O
Isomeric SMILES:C1COCC(=O)N1C2=CC=C(C=C2)NC[C@H](CN3C(=O)C4=CC=CC=C4C3=O)O
Uses 4-[((2R)-Hydroxy-3-phthalimido)propylamine]phenyl-3-morpholinone is a Rivaroxaban (R538000(P)) intermediate. Rivaroxaban is a novel antithrombotic agent. It is also a highly potent and selective, direct FXa inhibitor. Rivaroxaban intermediate.

Technology Process of (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione

There total 14 articles about (R)-2-(2-Hydroxy-3-((4-(3-oxomorpholino)phenyl)amino)propyl)isoindoline-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%