3-O-Methylquercetin tetraacetate

Base Information

• Chemical Name: 3-O-Methylquercetin tetraacetate
• CAS No.: 1486-69-7
• Molecular Formula: C₂₄H₂₀O₁₁
• Molecular Weight: 484.416
• Mol file: 1486-69-7.mol

Synonyms:3-O-Methylquercetintetraacetate; Quercetin 3-O-methyl ether peracetate

Chemical Property of 3-O-Methylquercetin tetraacetate

Chemical Property:

• PSA: 144.64000
• LogP: 3.16980

Purity/Quality:

98% ^*data from raw suppliers

3-O-Methylquercetintetraacetate ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-O-Methylquercetin tetraacetate

There total 7 articles about 3-O-Methylquercetin tetraacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-methoxy-chromen-4-on (1486-70-0) + acetic anhydride (108-24-7) → 3-O-methylquercetin 5,7,3',4'-O-tetraacetate (1486-69-7)

Guidance literature:

With pyridine;

Reference yield:

2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone (55317-02-7) → 3-O-methylquercetin 5,7,3',4'-O-tetraacetate (1486-69-7)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylamine / 165 °C / Erwaermen des Reaktionsprodukts mit wss.-aethanol. Kalilauge

2: pyridine

With pyridine; triethylamine;

Reference yield:

3,4-Dihydroxybenzoic acid (99-50-3) → 3-O-methylquercetin 5,7,3',4'-O-tetraacetate (1486-69-7)

Guidance literature:

Multi-step reaction with 5 steps

1: aq. NaOH solution

2: thionyl chloride

3: diethyl ether; pyridine

4: triethylamine / 165 °C / Erwaermen des Reaktionsprodukts mit wss.-aethanol. Kalilauge

5: pyridine

With pyridine; sodium hydroxide; thionyl chloride; diethyl ether; triethylamine;

upstream raw materials:

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-3-methoxy-chromen-4-on

acetic anhydride

2-methoxy-1-(2,4,6-trihydroxyphenyl)ethanone

3,4-Dihydroxybenzoic acid

Refernces

• 1、 Chumbalov et al.. "-". . . Retrieved 1969.
• 2、 Rubio, Sara,Quintana, Jose,Lopez, Mariana,Eiroa, Jose Luis,Triana, Jorge,Estevez, Francisco. "Phenylbenzopyrones structure-activity studies identify betuletol derivatives as potential antitumoral agents". . p. 9 - 20. Retrieved 2007/10/03.