2-ACETAMIDO-5-METHYLBENZENESULFONYL CHLORIDE

Base Information

• Chemical Name: 2-ACETAMIDO-5-METHYLBENZENESULFONYL CHLORIDE
• CAS No.: 116436-09-0
• Molecular Formula: C₉H₁₀ClNO₃S
• Molecular Weight: 247.702
• Mol file: 116436-09-0.mol

Synonyms:

Chemical Property of 2-ACETAMIDO-5-METHYLBENZENESULFONYL CHLORIDE

Chemical Property:

• Melting Point: 125 °C(Solv: benzene (71-43-2))
• Boiling Point: 433.3±38.0 °C(Predicted)
• PKA: 13.66±0.70(Predicted)
• Density: 1.411±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

2-(Acetylamino)-5-methylbenzenesulfonylChloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-ACETAMIDO-5-METHYLBENZENESULFONYL CHLORIDE

There total 2 articles about 2-ACETAMIDO-5-METHYLBENZENESULFONYL CHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-Methylacetanilide (103-89-9) → 4-acetylamino-toluene-3-sulfonyl chloride (116436-09-0)

Guidance literature:

With chlorosulphuric acid;

Reference yield:

2-Amino-5-methylbenzenesulfonic acid (88-44-8) + acetic anhydride (108-24-7) → 4-acetylamino-toluene-3-sulfonyl chloride (116436-09-0)

Guidance literature:

With phosphorus pentachloride; phosphorus trichloride;

Reference yield:

4-acetylamino-toluene-3-sulfonyl chloride (116436-09-0) → 4-acetylamino-toluene-3-sulfonic acid amide (855941-97-8)

Guidance literature:

With ammonia;

upstream raw materials:

2-Amino-5-methylbenzenesulfonic acid

acetic anhydride

4-Methylacetanilide

Downstream raw materials:

4-acetylamino-toluene-3-sulfonic acid amide

N-{2-[3-(4-Acetylamino-phenyl)-5-(4-methoxy-phenyl)-4,5-dihydro-pyrazole-1-sulfonyl]-4-methyl-phenyl}-acetamide

4-amino-3-sulfamoylbenzoic acid