Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH

Base Information

• Chemical Name: Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH
• CAS No.: 915098-66-7
• Molecular Formula: C₃₀H₄₇N₅O₁₀Si
• Molecular Weight: 665.816
• Mol file: 915098-66-7.mol

Synonyms:

Chemical Property of Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH

There total 1 articles about Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(fluoren-9-ylmethoxycarbonyl)glycine (29022-11-5) + N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine (35661-39-3,136132-75-7) + N-Fmoc-Tyr-OH (112883-29-1,92954-90-0) + N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-threonine (146346-82-9) → Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH (915098-66-7)

Guidance literature:

Multistep reaction.;

DOI:10.1039/b608544j

Reference yield:

Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH (915098-66-7) + 2-chlorotrityl chloride (42074-68-0) → C49H60ClN5O10Si (915098-67-8)

Guidance literature:

Alloc-Gly-Ala-Tyr-Thr(TBS)-Gly-OH; With caesium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.166667h;

2-chlorotrityl chloride; In N,N-dimethyl-formamide; at 20 ℃; for 1h; Further stages.;

DOI:10.1039/b608544j

upstream raw materials:

N-(fluoren-9-ylmethoxycarbonyl)glycine

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

N-Fmoc-Tyr-OH

N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-L-threonine

Downstream raw materials:

C₄₉H₆₀ClN₅O₁₀Si

Refernces