LY2811376

Base Information

• Chemical Name: LY2811376
• CAS No.: 1194044-20-6
• Molecular Formula: C15H14F2N4S
• Molecular Weight: 320.36
• Mol file: 1194044-20-6.mol

Synonyms:(4S)-4-[2,4-Difluoro-5-(5-pyrimidinyl)phenyl]-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine;(S)-4-(2,4-Difluoro-5-(pyrimidin-5-yl)phenyl)-4-methyl-5,6-dihydro-4H-1,3-thiazin-2-amine;

Chemical Property of LY2811376

Chemical Property:

• Boiling Point: 486.513 °C at 760 mmHg
• PKA: 5.60±0.40(Predicted)
• Flash Point: 248.034 °C
• Density: 1.428 g/cm³
• Solubility.: Soluble in DMSO

Purity/Quality:

98%,99%, ^*data from raw suppliers

LY 2811376 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: LY 281137 is a compound capable of the decrease in β-amyloid peptide (Aβ) associated with the cleavage of amyloid precursor protein (APP) by β-secretase (BACE) and γ-secretase. This decrease is important as its hypothesized that the build up of (Aβ) in the brain is a primary cause of neurodegeneration and Alzheimer’s progression.