4-Bromo-4'-iodobiphenyl

Base Information

• Chemical Name: 4-Bromo-4'-iodobiphenyl
• CAS No.: 105946-82-5
• Molecular Formula: C12H8BrI
• Molecular Weight: 359.004
• Hs Code.: 29039990
• DSSTox Substance ID: DTXSID00447855
• Nikkaji Number: J1.090.128F
• Wikidata: Q72457511
• Mol file: 105946-82-5.mol

Synonyms:4-Bromo-4’-iodobiphenyl;

Chemical Property of 4-Bromo-4'-iodobiphenyl

Chemical Property:

• Appearance/Colour: White powder
• Melting Point: 166-168 °C
• Boiling Point: 369.329 °C at 760 mmHg
• Flash Point: 177.164 °C
• PSA: 0.00000
• Density: 1.86 g/cm³
• LogP: 4.72070
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Sensitive.: Light Sensitive
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 357.88541
• Heavy Atom Count: 14
• Complexity: 167

Purity/Quality:

99.5% ^*data from raw suppliers

4-Bromo-4''-iodobiphenyl ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38-52/53
• Safety Statements: 26-37-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)I)Br
• Uses: suzuki reaction

Technology Process of 4-Bromo-4'-iodobiphenyl

There total 10 articles about 4-Bromo-4'-iodobiphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

4-bromo-1,1'-biphenyl (92-66-0) → 4-bromo-4'-iodobiphenyl (105946-82-5)

Guidance literature:

With periodic acid dihydrate; sulfuric acid; iodine; acetic acid; at 65 - 90 ℃; for 6.5h; Inert atmosphere;

Reference yield: 90.0%

4-bromo-4'-(diacetoxyiodo)biphenyl (919474-54-7) → 4-bromo-4'-iodobiphenyl (105946-82-5)

Guidance literature:

With sulfuric acid; 4'-methylpropiophenone; trimethyl orthoformate; at 60 ℃; for 2h;

DOI:10.1016/j.tet.2006.09.112

Reference yield: 70.0%

→ 4-bromo-4'-iodobiphenyl (105946-82-5)

Guidance literature:

With periodic acid dihydrate; iodine; In sulfuric acid; water; acetic acid; at 65 - 90 ℃; for 6.5h; Inert atmosphere;

upstream raw materials:

4-bromo-1,1'-biphenyl

iodobenzene

1,6-di-p-bromophenyl-3,4-diacetyl-1,5-hexazadiene

4-bromo-4'-(diacetoxyiodo)biphenyl

Downstream raw materials:

(R)-2-(1-(4'-bromobiphenyl-4-yl)vinyl)tetrahydrofuran

3-(4'-bromo-[1,1'-biphenyl]-4-yl)-9-phenyl-9H-carbazole

9-(4’-bromo-[1,1‘-biphenyl]-4-yl)-9H-carbazole

C₆₉H₅₆Br₂N₂

Refernces

• 1、 Wang, Denan,Talipov, Marat R.,Ivanov, Maxim V.,Rathore, Rajendra. "Energy Gap between the Poly-p-phenylene Bridge and Donor Groups Controls the Hole Delocalization in Donor-Bridge-Donor Wires". . p. 16337 - 16344. Retrieved 2016.
• 2、 Li, Hong-Liang,Kuninobu, Yoichiro. "Palladium-Catalyzed Secondary C(sp3)?H Arylation of 2-Alkylpyridines". supporting information. p. 2637 - 2641. Retrieved 2020/06/02.