O-Acetyl Pseudoephedrine Hydrochloride

Base Information

• Chemical Name: O-Acetyl Pseudoephedrine Hydrochloride
• CAS No.: 1630-34-8
• Molecular Formula: C₁₂H₁₇NO₂*ClH
• Molecular Weight: 243.733
• Mol file: 1630-34-8.mol

Synonyms:

Chemical Property of O-Acetyl Pseudoephedrine Hydrochloride

Chemical Property:

• Melting Point: 187 °C

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: O-Acetyl Pseudoephedrine is the O-acetylated analogue of the non-selective adrenergic agonist Pseudoephedrine (P839350).

Technology Process of O-Acetyl Pseudoephedrine Hydrochloride

There total 7 articles about O-Acetyl Pseudoephedrine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-ephedrine hydrochloride (134-71-4) + acetyl chloride (75-36-5) → (1RS:2SR)-2-methylamino-1-acetoxy-1-phenyl-propane; hydrochloride (1630-34-8,14383-62-1,95469-47-9)

Guidance literature:

With hydrogenchloride; acetic acid;

DOI:10.1007/BF00898985

Reference yield:

acetic anhydride (108-24-7) + rac-ephedrine hydrochloride (134-71-4) + acetyl chloride (75-36-5) → (1RS:2SR)-2-methylamino-1-acetoxy-1-phenyl-propane; hydrochloride (1630-34-8,14383-62-1,95469-47-9)

Guidance literature:

DOI:10.1021/ja01193a036

Reference yield:

(±)-pseudoephedrine hydrochloride (50-98-6,134-71-4,345-78-8,670-40-6,24221-86-1,56979-55-6,63991-26-4,77262-74-9,77274-98-7) + acetyl chloride (75-36-5) → acetic acid-((1RS,2RS)-2-methylamino-1-phenyl-propylester); hydrochloride (1630-34-8,14383-62-1,95469-47-9)

Guidance literature:

With hydrogenchloride; acetic acid;

DOI:10.1007/BF00898985

upstream raw materials:

acetic anhydride

ephedrine hydrochloride

Novafed

acetyl chloride

Downstream raw materials:

(1S,2S)-N-<(2-Hydroxy-2-phenyl)-1-methyl-ethyl>-N-methylacetamid

N-((1RS,2SR)-2-hydroxy-1-methyl-2-phenyl-ethyl)-N-methyl-acetamide