methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate

Base Information

• Chemical Name: methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate
• CAS No.: 77651-56-0
• Molecular Formula: C₁₁H₁₃NO₃S
• Molecular Weight: 239.295
• Mol file: 77651-56-0.mol

Synonyms:

Chemical Property of methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate

There total 3 articles about methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl thioformate (29392-46-9) + 2-methoxy phenylglycine methyl ester (77651-55-9) → methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate (77651-56-0)

Guidance literature:

With hydrogen sulfide;

Reference yield:

5-(2-methoxyphenyl)imidazolidine-2,4-dione (77651-54-8) → methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate (77651-56-0)

Guidance literature:

Multi-step reaction with 3 steps

1: 52 percent / aq. NAOH

2: 74 percent / aq. HCl

3: 85 percent / H₂S

With hydrogenchloride; sodium hydroxide; hydrogen sulfide;

Reference yield:

2-amino-2-(2-methoxyphenyl)acetic acid (271583-17-6,103889-84-5,103889-86-7) → methyl (+/-)-2-methoxy-α-<(thioxomethyl)amino>benzene acetate (77651-56-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 74 percent / aq. HCl

2: 85 percent / H₂S

With hydrogenchloride; hydrogen sulfide;

upstream raw materials:

ethyl thioformate

2-methoxy phenylglycine methyl ester

5-(2-methoxyphenyl)imidazolidine-2,4-dione

2-amino-2-(2-methoxyphenyl)acetic acid

Downstream raw materials:

(2-Methoxy-phenyl)-methylsulfanylmethyleneamino-acetic acid methyl ester

Refernces