4-Chlorobenzenesulfonothioic acid S-phenyl ester

Base Information

• Chemical Name: 4-Chlorobenzenesulfonothioic acid S-phenyl ester
• CAS No.: 1142-97-8
• Molecular Formula: C12H9ClO2S2
• Molecular Weight: 284.787
• Hs Code.: 2930909090
• Mol file: 1142-97-8.mol

Synonyms:S-phenyl 4-chlorobenzenesulfonothioate;phenyl 4-chlorobenzenethiosulfonate;Benzenesulfonothioic acid,4-chloro-,S-phenyl ester;4-Chlor-benzol-1-thiosulfonsaeure-S-phenylester;4-chloro-benzenesulfonothioic acid,S-phenyl ester;Benzenesulfonothioic acid, 4-chloro-, S-phenyl ester;S-phenyl p-chlorobenzenethiosulphonate;Benzenesulfonic acid,p-chlorothio-,S-phenyl ester;4-Chlor-benzolthiosulfonsaeure-S-phenylester;4-chloro-benzenethiosulfonic acid S-phenyl ester;

Chemical Property of 4-Chlorobenzenesulfonothioic acid S-phenyl ester

Chemical Property:

• Melting Point: -86.8°C
• Refractive Index: 1.4087
• PSA: 67.82000
• Density: 0.8341
• LogP: 4.90180

Purity/Quality:

98%,99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Chlorobenzenesulfonothioic acid S-phenyl ester

There total 9 articles about 4-Chlorobenzenesulfonothioic acid S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

p-chlorophenylsulfonyl hydrazide (2751-25-9) + thiophenol (108-98-5) → phenyl 4-chlorobenzenethiosulfonate (1142-97-8)

Guidance literature:

With tert.-butylhydroperoxide; copper(ll) bromide; In acetonitrile; at 80 ℃; for 2h; Schlenk technique;

DOI:10.1021/acs.joc.7b01121

Reference yield: 75.0%

sodium p-chlorobenzenesulphinate (14752-66-0) + diphenyldisulfane (882-33-7) → phenyl 4-chlorobenzenethiosulfonate (1142-97-8)

Guidance literature:

With N-Bromosuccinimide; In acetonitrile; at 25 ℃; for 15h;

DOI:10.1002/cjoc.201200028

Reference yield: 73.0%

p-chlorophenylsulfonyl hydrazide (2751-25-9) + diphenyldisulfane (882-33-7) → phenyl 4-chlorobenzenethiosulfonate (1142-97-8)

Guidance literature:

With dihydrogen peroxide; In water; at 100 ℃; for 2h; Schlenk technique; Green chemistry;

DOI:10.1039/c8gc00381e

upstream raw materials:

diphenyliodonium chloride

4-chloro-benzenethiosulfonic acid ; potassium-salt

benzenesulfenyl chloride

sodium p-chlorobenzenesulphinate

Downstream raw materials:

4-chlorobenzenesulfinic acid

phenyl N,N-dimethyl(thiocarbamate)

3-(phenylthio)pentane-2,4-dione

sodium p-chlorobenzenesulphinate

Refernces

• 1、 Bi, Wen-Zhu,Zhang, Wen-Jie,Li, Zi-Jie,He, Yuan-Hao,Feng, Su-Xiang,Geng, Yang,Chen, Xiao-Lan,Qu, Ling-Bo. "Visible-light-promoted synthesis of secondary and tertiary thiocarbamates from thiosulfonates andN-substituted formamides". supporting information. p. 8701 - 8705. Retrieved 2021/10/22.
• 2、 Wang, Fei,Liu, Bo-Xi,Rao, Weidong,Wang, Shun-Yi. "Metal-Free Chemoselective Reaction of Sulfoxonium Ylides and Thiosulfonates: Diverse Synthesis of 1,4-Diketones, Aryl Sulfursulfoxonium Ylides, and β-Keto Thiosulfones Derivatives". supporting information. p. 6600 - 6604. Retrieved 2020/09/02.