C₃₁H₃₆N₄O₇S

Base Information

• Chemical Name: C₃₁H₃₆N₄O₇S
• CAS No.: 1245739-50-7
• Molecular Formula: C₃₁H₃₆N₄O₇S
• Molecular Weight: 608.715
• Mol file: 1245739-50-7.mol

Synonyms:

Chemical Property of C₃₁H₃₆N₄O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₃₆N₄O₇S

There total 10 articles about C₃₁H₃₆N₄O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-Benzoxazolinone (59-49-4) → C31H36N4O7S (1245739-50-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / benzene

2: hydrogenchloride; water / 1,4-dioxane

3: 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / acetonitrile / Inert atmosphere

With 4-methyl-morpholine; hydrogenchloride; water; sodium hydride; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In 1,4-dioxane; acetonitrile; benzene;

DOI:10.1111/j.1747-0285.2010.00995.x

Reference yield:

Phenylmethyl [2R-hydroxy-3-[(2-methylpropyl)(4-acetamidophenylsulfonyl)amino]-1S-(phenylmethyl)propyl]carbamate → C31H36N4O7S (1245739-50-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 10% palladium on activated charcoal; ammonium formate / methanol

2: 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / acetonitrile / Inert atmosphere

With 4-methyl-morpholine; 10% palladium on activated charcoal; ammonium formate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; In methanol; acetonitrile;

DOI:10.1111/j.1747-0285.2010.00995.x

Reference yield:

N-Cbz-L-Phe (1161-13-3) → C31H36N4O7S (1245739-50-7)

Guidance literature:

Multi-step reaction with 7 steps

1.1: 4-methyl-morpholine; isobutyl chloroformate / tetrahydrofuran / -20 °C

1.2: -20 °C

2.1: hydrogenchloride / diethyl ether / -20 °C

3.1: lithium tri-t-butoxyaluminum hydride / ethanol / -78 °C

4.1: isopropyl alcohol / 70 °C

5.1: sodium hydrogencarbonate / water; 1,2-dichloro-ethane

6.1: 10% palladium on activated charcoal; ammonium formate / methanol

7.1: 4-methyl-morpholine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate / acetonitrile / Inert atmosphere

With 4-methyl-morpholine; hydrogenchloride; 10% palladium on activated charcoal; ammonium formate; sodium hydrogencarbonate; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; lithium tri-t-butoxyaluminum hydride; isobutyl chloroformate; In tetrahydrofuran; methanol; diethyl ether; ethanol; water; 1,2-dichloro-ethane; isopropyl alcohol; acetonitrile;

DOI:10.1111/j.1747-0285.2010.00995.x

upstream raw materials:

2-Benzoxazolinone

2-[2-oxo-benzo[d]oxazole-3(2H)-yl]acetic acid

N-Cbz-L-Phe

(S)-3-[(benzyloxycarbonyl)amino]-1-diazo-4-phenyl-2-butanone

Refernces