1-Fluorooctadecane

Base Information

• Chemical Name: 1-Fluorooctadecane
• CAS No.: 1649-73-6
• Molecular Formula: C18H37F
• Molecular Weight: 272.49
• DSSTox Substance ID: DTXSID80521824
• Nikkaji Number: J2.154.184B
• Wikidata: Q82386566
• Mol file: 1649-73-6.mol

Synonyms:1-FLUOROOCTADECANE;1649-73-6;SCHEMBL19221488;DTXSID80521824

Chemical Property of 1-Fluorooctadecane

Chemical Property:

• XLogP3: 9.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 16
• Exact Mass: 272.28792934
• Heavy Atom Count: 19
• Complexity: 145

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCF

Technology Process of 1-Fluorooctadecane

There total 4 articles about 1-Fluorooctadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

octadecyltrichlorosilane (112-04-9) → octadec-1-ene (112-88-9) + 1-fluorooctadecane (1649-73-6)

Guidance literature:

With iodine; cesium fluoride; In N,N-dimethyl-formamide; at 100 ℃; for 20h; Inert atmosphere; Schlenk technique; Sealed tube;

DOI:10.1021/acs.orglett.9b02695

Reference yield:

n-iodooctadecane (629-93-6) → octadec-1-ene (112-88-9) + 1-fluorooctadecane (1649-73-6)

Guidance literature:

With tetrabutylammonium hydrogen bifluoride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 95 ℃; for 2.5h;

DOI:10.1016/S0040-4039(00)96612-7

Reference yield:

1-Bromooctadecane (112-89-0) → octadec-1-ene (112-88-9) + 1-fluorooctadecane (1649-73-6)

Guidance literature:

With tetrabutylammonium hydrogen bifluoride; In tetrahydrofuran; N,N,N,N,N,N-hexamethylphosphoric triamide; at 95 ℃; for 5h;

DOI:10.1016/S0040-4039(00)96612-7

upstream raw materials:

n-iodooctadecane

1-Bromooctadecane

octadecyltrichlorosilane

Refernces

• 1、 Maeda, Hatsuo,Koide, Takashi,Matsumoto, Sayaka,Ohmori, Hidenobu. "Fluorination of secondary and primary alcohols by thermal decomposition of electrochemically generated alkoxy triphenylphosphonium tetrafluoroborates". . p. 1480 - 1483. Retrieved 2007/10/03.