2,6-Dimethyl-3,5-dicyanopyridine

Base Information

• Chemical Name: 2,6-Dimethyl-3,5-dicyanopyridine
• CAS No.: 1656-95-7
• Molecular Formula: C9H7N3
• Molecular Weight: 157.17200
• Hs Code.: 2933399090
• Mol file: 1656-95-7.mol

Synonyms:3,5-Dicyan-2,6-lutidin;2,6-Dimethyl-pyridin-3,5-dicarbonitril;2,6-Dimethyl-3,5-dicyan-pyridin;2,6-dimethyl-pyridine-3,5-dicarbonitrile;2,6-Dimethyl-3,5-dicyano-pyridin;3,5-Pyridinedicarbonitrile,2,6-dimethyl;2,6-Dimethyl-3,5-dicyanopyridine;AmbscPOD_44/0857;3,5-dicyano-2,6-dimethylpyridine;

Chemical Property of 2,6-Dimethyl-3,5-dicyanopyridine

Chemical Property:

• PSA: 60.47000
• LogP: 1.44176

Purity/Quality:

95% ^*data from raw suppliers

2,6-DIMETHYL-3,5-PYRIDINEDICARBONITRILE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-Dimethyl-3,5-dicyanopyridine

There total 12 articles about 2,6-Dimethyl-3,5-dicyanopyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

3-Aminocrotononitrile (1118-61-2) + orthoformic acid triethyl ester (122-51-0) → 3,5-dicyano-2,6-dimethylpyridine (1656-95-7)

Guidance literature:

With hafnium(IV) trifluoromethanesulfonate; In chloroform; at 60 ℃; for 3h; Inert atmosphere; sealed vial;

DOI:10.1055/s-0030-1260978

Reference yield: 57.0%

2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarbonitrile (3274-36-0) → 3,5-dicyano-2,6-dimethylpyridine (1656-95-7)

Guidance literature:

With benzofurazan oxide; In ethanol; acetonitrile; for 10h; Heating;

DOI:10.1080/00397919208021304

Reference yield: 50.0%

acetonitrile (75-05-8,26809-02-9) → 2,6-dimethylpyridine-3,4,5-tricarbonitrile (872336-73-7) + 3,5-dicyano-2,6-dimethylpyridine (1656-95-7) + 2,4,6-trimethylpyridine-3,5-dicarbonitrile (1539-48-6)

Guidance literature:

With tetra(n-butyl)ammonium hydrogensulfate; Further Variations:; circulated charge; current density; Product distribution; Electrochemical reaction;

DOI:10.1016/j.tetlet.2005.10.059

upstream raw materials:

2,6-dimethyl-1,4-dihydro-pyridine-3,5-dicarbonitrile

C₃₈H₃₀N₈

α,α-Diphenyl-β-(2,4,6-tricyanophenyl)-hydrazyl

1,3,5-(2,4,6-Tricyanobenzotriyl)tris(N¹,N¹-diphenylhydrazyl)-Triradikal

Refernces

• 1、 Sasada, Toshiaki,Kobayashi, Fuminori,Moriuchi, Masato,Sakai, Norio,Konakahara, Takeo. "An oxidant-free single-step synthesis of tetra-or disubstituted symmetrical pyridine derivatives by a Hf(OTf)4-catalyzed annulation". supporting information; experimental part. p. 2029 - 2034. Retrieved 2011/10/09.
• 2、 Patzold,Zeuner,Heyer,Niclas. "Dehydrogenations using benzofuroxan as oxidant". . p. 281 - 288. Retrieved 2007/10/02.