Phenamidine

Base Information

• Chemical Name: Phenamidine
• CAS No.: 101-62-2
• Molecular Formula: C14H14 N4 O
• Molecular Weight: 254.291
• European Community (EC) Number: 202-960-8
• UNII: 382086V7IB
• DSSTox Substance ID: DTXSID10143619
• Nikkaji Number: J182.146F
• Wikipedia: Phenamidine
• Wikidata: Q2085485
• ChEMBL ID: CHEMBL588339
• Mol file: 101-62-2.mol

Synonyms:di(4-amidinophenyl)ether;phenamidine;phenamidine dihydrochloride

Chemical Property of Phenamidine

Chemical Property:

• Melting Point: 215-216°
• Boiling Point: 411.3°Cat760mmHg
• Flash Point: 202.5°C
• PSA: 108.97000
• Density: 1.3g/cm³
• LogP: 3.64710
• XLogP3: 1.4
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 254.11676108
• Heavy Atom Count: 19
• Complexity: 296

Purity/Quality:

98%,99%, ^*data from raw suppliers

4,4'-DIBENZAMIDINE OXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C(=N)N)OC2=CC=C(C=C2)C(=N)N

Technology Process of Phenamidine

There total 3 articles about Phenamidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(4'-cyanophenoxy)benzonitrile (6508-04-9) → 4,4'-oxydibenzimidamine (101-62-2)

Guidance literature:

With ammonium thiocyanate; at 180 ℃;

DOI:10.1039/jr9470000390

Reference yield:

benzenesulfonamide (98-10-2) + oxybis(benzoic acid) (2215-89-6) → 4,4'-oxydibenzimidamine (101-62-2)

Guidance literature:

With benzenesulfonic acid; at 220 - 240 ℃; Leiten von Ammoniak ueber das Reaktionsgemisch bei 220grad und anschliessenden Erhitzen auf 260-265grad;

Reference yield:

→ 4,4'-oxydibenzimidamine (101-62-2)

Guidance literature:

Bis-<4-cyano-phenyl>-oxyd, NH3, K;

upstream raw materials:

benzenesulfonamide

oxybis(benzoic acid)

4-(4'-cyanophenoxy)benzonitrile

Refernces