4-Bromo-4'-chloro-1,1'-biphenyl

Base Information

• Chemical Name: 4-Bromo-4'-chloro-1,1'-biphenyl
• CAS No.: 23055-77-8
• Molecular Formula: C12H8BrCl
• Molecular Weight: 267.553
• Hs Code.: 2902900000
• European Community (EC) Number: 811-890-2,940-956-4
• Nikkaji Number: J901.749F
• Mol file: 23055-77-8.mol

Synonyms:4-bromo-4'-chloro-1,1'-biphenyl;23055-77-8;4-BROMO-4'-CHLOROBIPHENYL;1-bromo-4-(4-chlorophenyl)benzene;1,1'-Biphenyl, 4-bromo-4'-chloro-;1-(4-BROMOPHENYL)-4-CHLOROBENZENE;4'-chloro-4-bromo-biphenyl;4-Chloro-4'-bromobiphenyl;SCHEMBL3869855;WMXVUHANYJZYHO-UHFFFAOYSA-N;AKOS004117399;AS-2149;SB66841;AM805351;B5966;CS-0148348;A853081

Chemical Property of 4-Bromo-4'-chloro-1,1'-biphenyl

Chemical Property:

• Melting Point: 147 °C
• Boiling Point: 337.9±17.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.463±0.06 g/cm3(Predicted)
• LogP: 4.76950
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 5.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 265.94979
• Heavy Atom Count: 14
• Complexity: 167

Purity/Quality:

98% ^*data from raw suppliers

4-bromo-4''-chloro-1,1''-biphenyl ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1C2=CC=C(C=C2)Br)Cl

Technology Process of 4-Bromo-4'-chloro-1,1'-biphenyl

There total 25 articles about 4-Bromo-4'-chloro-1,1'-biphenyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

bromochlorobenzene (106-39-8) + 4-Bromophenylboronic acid (5467-74-3) → 4'-chloro-4-bromo-biphenyl (23055-77-8)

Guidance literature:

With potassium carbonate; In ethyl acetate; at 90 ℃; for 1.5h; Catalytic behavior;

DOI:10.1002/aoc.5172

Reference yield: 90.0%

p-chlorobenzenediazonium tetrafluoroborate (673-41-6) + potassium 4-bromophenyltrifluoroborate (374564-35-9) → 4'-chloro-4-bromo-biphenyl (23055-77-8)

Guidance literature:

With alginate/gellan gum beads containing Pd nanoparticles; In water; at 40 ℃; for 24h;

DOI:10.1039/c2gc15679b

Reference yield: 85.0%

1,4-bromoiodobenzene (589-87-7) + 4-Chlorophenylboronic acid (1679-18-1) → 4'-chloro-4-bromo-biphenyl (23055-77-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 1h;

DOI:10.1016/j.catcom.2015.05.013

upstream raw materials:

4-bromo-1,1'-biphenyl

4-amino-4'-bromobiphenyl

4'-biphenyl chloride

bromobenzene

Downstream raw materials:

(4'-chloro-biphenyl-4-yl)-trimethyl-silane

p-(p'Chlorphenyl)trifluoracetophenon

(4’-chloro-[1,1’-biphenyl]-4-yl)boronic acid

C₃₆H₂₇ClN₂

Refernces

• 1、 -. "Aromatic amine derivative organic electroluminescent material and device thereof". Paragraph 0143-0146. . Retrieved 2021/09/29.
• 2、 Wang, Fengze,Wang, Chen,Sun, Guoping,Zou, Gang. "Highly efficient palladium-catalyzed cross-coupling of diarylborinic acids with arenediazoniums for practical diaryl synthesis". supporting information. . Retrieved 2019/12/25.