100-88-9 Usage
Description
Cyclamic acid, also known as N-cyclohexylsulfamic acid, is a member of the sulfamic acid class that carries an N-cyclohexyl substituent. It is a white solid with a well-known therapeutic application and is commonly referred to by its brand name, Hexamic Acid.
Uses
Used in Pharmaceutical Industry:
Cyclamic acid is used as a non-nutritive sweetener for its therapeutic applications. It is particularly useful in the development of N-cyclohexylsulfamic acid salts of well-known therapeutic agents, enhancing their effectiveness and utility in the medical field.
Used in Food Industry:
As a non-nutritive sweetener, Cyclamic acid is also utilized in the food industry to provide sweetness without adding calories or nutritional value, making it a suitable option for those seeking to reduce their sugar intake or for individuals with diabetes.
Flammability and Explosibility
Notclassified
Safety Profile
Suspected human
carcinogen producing bladder tumors.
Poison by intravenous route. LWdly toxic by
ingestion. When heated to decomposition it
emits toxic fumes of SOx and NOx.
Check Digit Verification of cas no
The CAS Registry Mumber 100-88-9 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,0 and 0 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 100-88:
(5*1)+(4*0)+(3*0)+(2*8)+(1*8)=29
29 % 10 = 9
So 100-88-9 is a valid CAS Registry Number.
InChI:InChI=1/C6H13NO3S/c8-11(9,10)7-6-4-2-1-3-5-6/h6-7H,1-5H2,(H,8,9,10)
100-88-9Relevant articles and documents
N-alkylated sulfamic acid derivatives as organocatalyst in multicomponent synthesis of fatty dihydropyrimidinones
Hack, Carolina R. L.,Porciuncula, Larissa,Weber, Andressa C. H.,D’Oca, Caroline R. M.,Russowsky, Dennis,Moura, Jaqueline M.,Pinto, Luiz A. A.,D’Oca, Marcelo G. M.
, p. 2342 - 2349 (2018)
In this work, N-alkylated sulfamic acid derivatives are introduced as promising acidic organocatalysts with convenient acidity and easy synthesis. The new organocatalysts derived from different nitrogenated compounds (amines, chitosan, urea and thiourea) were applied in multicomponent reactions to synthesize several dihydropyrimidinones (DHPMs). All tested organocatalysts resulted in good DHPM yields, using classic 1,3-dicarbonyl compounds and long-chain 1,3-dicarbonyl derivatives, demonstrating catalytic efficiency. N-Alkylated sulfamic acid derived from benzylamine showed good results (ca. 80percent yields). In addition, excellent results were obtained with organocatalysts based on sulfamic acid and thiourea (ca. 80-97percent yields), demonstrating the catalytic efficiency of new derivatives of thiourea organosulfamic catalysts.
Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds
-
, (2008/06/13)
New condensed diazepinones of general formula I are described STR1 wherein B represents one of the divalent groups STR2 and X1, X2, A, R1 to R10 and Z are defined as in the specification.