1001011-80-8

Basic information

• Product Name: (4-fluoro-phenylimino)-acetic acid ethyl ester
• Synonyms: (4-fluoro-phenylimino)-acetic acid ethyl ester
• CAS NO: 1001011-80-8
• Molecular Weight: 195.193
• Mol File: 1001011-80-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: (4-fluoro-phenylimino)-acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-fluoro-phenylimino)-acetic acid ethyl ester(1001011-80-8)
• EPA Substance Registry System: (4-fluoro-phenylimino)-acetic acid ethyl ester(1001011-80-8)

Safety Data

• Hazardous Substances Data: 1001011-80-8(Hazardous Substances Data)

Upstream product

• 924-44-7 glyoxylic acid ethyl ester 
• 371-40-4 4-fluoroaniline 
• 2521-99-5 2-(4-fluorophenylamino)acetic acid ethyl ester 

Relevant articles and documents

Tin powder-promoted oxidation/allylation of glycine esters: Synthesis of γ,δ-unsaturated α-amino acid esters

An efficient tin powder-promoted oxidation/allylation reaction of glycine esters with allyl bromides is developed, which affords γ,δ-unsaturated α-amino acid esters under mild conditions without any other transition metal catalysts. This method avoids the use of unstable imine as starting material, and provides an efficient method for synthesis of γ,δ-unsaturated α-amino acid esters and α-methylene-γ-lactam derivatives. Additional supporting information may be found in the online version of this article at the publisher's web site.

Polarity-Reversed Addition of Enol Ethers to Imines under Visible Light: Redox-Neutral Access to Azide-Containing Amino Acids

A three-component and polarity-reversed addition cascade with a glyoxylate-based imine, an enol ether, and TMSN3 was established for the construction of γ-azido amino acids under visible light. This transformation features mild and redox-neutra

ALDOSTERONE SYNTHASE INHIBITORS

The present invention relates to compounds of formula I: and pharmaceutically acceptable salts thereof, wherein Cy, R1 and R2 are as defined herein. The invention also relates to pharmaceutical compositions comprising these compounds, methods of using these compounds in the treatment of various diseases and disorders, processes for preparing these compounds and intermediates useful in these processes.