101342-45-4

Basic information

• Product Name: 4-EPICHLORTETRACYCLINE HYDROCHLORIDE
• Synonyms: 4-EPICHLORTETRACYCLINE HYDROCHLORIDE;(4R,4aS,5aS,6S,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide Monohydrate;4-Epichlortetracycline Hydrochlorid;4-Epichlortetracycline hydrochloride, 97%, can be used as secondary standard;4-Epichlortetracycline hydrochlorideECTC;4-Epichlortetracycline hydrochloride, can be used as secondary standard, 97% 100MG;4-Epichlortetracycline hydrochloride, can be used as secondary standard, 97% 500MG;Epichlortetracycline hydrochloride
• CAS NO: 101342-45-4
• Molecular Formula: C22H23ClN2O8.ClH
• Molecular Weight: 515.344
• Product Categories: All Inhibitors;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
• Mol File: 101342-45-4.mol
• Article Data: 0

Chemical Properties

• Melting Point: >250°C
• Appearance: Pale yellow to orange/Powder
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
• Stability: Hygroscopic, Unstable in Solution
• CAS DataBase Reference: 4-EPICHLORTETRACYCLINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-EPICHLORTETRACYCLINE HYDROCHLORIDE(101342-45-4)
• EPA Substance Registry System: 4-EPICHLORTETRACYCLINE HYDROCHLORIDE(101342-45-4)

Safety Data

• Hazardous Substances Data: 101342-45-4(Hazardous Substances Data)

Usage

Description

4-EPICHLORTETRACYCLINE HYDROCHLORIDE is a Tetracycline derivative that is formed as a degradation product of chlorotetracycline through acid-catalysed isomerisation of the dimethylamino group at C4. It is characterized by its pale yellow to orange powder appearance and has little antibiotic activity. However, its presence is indicative of poor storage and handling of chlortetracycline.

Uses

Used in Pharmaceutical Industry:
4-EPICHLORTETRACYCLINE HYDROCHLORIDE is used as a metalloprotease inhibitor for treating tissue destructive diseases and cancer. Its application in this industry is due to its ability to inhibit the activity of metalloproteases, enzymes that play a crucial role in the degradation of tissues and the progression of certain diseases.
Used in Quality Control of Chlortetracycline Storage and Handling:
Although 4-EPICHLORTETRACYCLINE HYDROCHLORIDE has little antibiotic activity, its abundance can serve as an indicator of poor storage and handling practices for chlortetracycline. This makes it useful in ensuring the quality and efficacy of chlortetracycline products by monitoring the presence of this degradation product.