1018832-89-7Relevant articles and documents
Catalytic asymmetric aldol-type reaction of zinc enolate equivalent of amides
Haraguchi, Ryosuke,Matsubara, Seijiro
supporting information, p. 3378 - 3380 (2013/07/26)
Treatment of phenyl isocyanate with bis(iodozincio)methane gave a zinciomethylenated product, which acts as an amide-enoate equivalent. It did not react with an aldehyde efficiently, but gave the corresponding adduct in good yield in the presence of an aminoalcohol. Use of a catalytic amount of chiral aminoalcohol led the process to the catalytic asymmetric Aldol-type reaction.