1033810-73-9

Basic information

• Product Name: 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-chloroaniline
• Synonyms: 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-chloroaniline
• CAS NO: 1033810-73-9
• Molecular Formula: C₁₂H₉ClN₄O
• Molecular Weight: 260.67906
• EINECS: -0
• Mol File: 1033810-73-9.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-chloroaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-chloroaniline(1033810-73-9)
• EPA Substance Registry System: 4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)-3-chloroaniline(1033810-73-9)

Safety Data

• Hazardous Substances Data: 1033810-73-9(Hazardous Substances Data)

Upstream product

• 1053655-66-5 7-bromo-[1,2,4]triazolo[1,5-a]pyridine 
• 1033810-70-6 [1,2,4]triazolo[1,5-a]pyridin-7-ol 
• 350-30-1 3-chloro-4-fluoronitrobenzene 

Relevant articles and documents

ALKYNE QUINAZOLINE DERIVATIVES AS INHIBITORS OF ERBB2

The present disclosure relates generally to compounds and compositions thereof for inhibition of ErbB2, including mutant forms of ErbB2, particularly those harboring an Exon 20 mutation, methods of preparing said compounds and compositions, and their use in the treatment or prophylaxis of various cancers, such as lung, glioma, skin, head neck, salivary gland, breast, esophageal, liver, stomach (gastric), uterine, cervical, biliary tract, pancreatic, colorectal, renal, bladder or prostate cancer.

[1,3]DIAZINO[5,4-D]PYRIMIDINES AS HER2 INHIBITORS

The present invention relates to new [1,3]diazino[5,4-d]pyrimidines and derivatives of Formula (I) wherein the groups R1, R2, R3 and R4 have the meanings given in the claims and specification, their use as inhibitors of HER2 and its mutants, pharmaceutical compositions which contain such compounds and their use as medicaments, especially as agents for treatment and/or prevention of oncological diseases.