1035218-87-1

Basic information

• Product Name: 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one
• Synonyms: LSN-2606297;5-(4-(azetidin-3-yloxy)-3-Methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one;5-[4-(azetidin-3-yloxy)-3-methoxyphenyl]-2-(4-chlorophenyl)-[1,3]thiazolo[5,4-c]pyridin-4-one
• CAS NO: 1035218-87-1
• Molecular Formula: C22H18ClN3O3S
• Molecular Weight: 476.383
• Mol File: 1035218-87-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one(1035218-87-1)
• EPA Substance Registry System: 5-(4-(azetidin-3-yloxy)-3-methoxyphenyl)-2-(4-chlorophenyl)thiazolo[5,4-c]pyridin-4(5H)-one(1035218-87-1)

Safety Data

• Hazardous Substances Data: 1035218-87-1(Hazardous Substances Data)

Usage

Structure

Complex organic compound with a thiazole and pyridine ring system

Functional groups

Methoxy group (attached to the phenyl ring)
Chlorophenyl group (attached to the thiazole ring)
Azetidin-3-yloxy group (attached to the phenyl ring)

Bioactivity

Potential bioactivity suggested by the chemical structure

Applications

Pharmaceutical research: Potential for drug development
Chemical synthesis: Utilization in various synthetic processes
Material science: Possible applications in materials research

Properties

Thiazole and pyridine rings: Indicators of potential bioactivity and diverse applications
Complex structure: Requires further study and analysis for full understanding

Upstream product

• 1035219-47-6 3-(4-{[2-(4-chlorophenyl)-4-(2,2-dimethoxyethyl)thiazole-5-carbonyl]amino}-2-methoxyphenoxy)azetidine-1-carboxylic acid tert-butyl ester 
• 1035219-73-8 3-{4-[2-(4-chlorophenyl)-4-oxo-4H-thiazolo[5,4-c]pyridin-5-yl]-2-methoxyphenoxy}azetidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1035218-91-7 2-(4-chlorophenyl)-5-[3-methoxy-4-(1-methylazetidin-3-yloxy)phenyl]-5H-thiazolo[5,4-c]pyridin-4-one 

Relevant articles and documents

5- [4- (AZETIDIN-3-YL0XY) -PHENYL] -2-PHENYL-5H-THIAZ0L0 [5,4-C] PYRIDIN-4-0NE DERIVATIVES AND THEIR USE AS MCH RECEPTOR ANTAGONISTS

The present invention relates to a melanin concentrating hormone antagonist compound of formula I: wherein "-----" is absent or is optionally a bond; q is 1 or 2; R1 is independently selected from hydrogen, -C1-C2 alkyl, halo, hydroxy, -C1-C2 haloalkyl, -C1-C3 alkoxy, cyano, -O-C3-C4 cycloalkyl, and -OC1-C2 haloalkyl; R2 is selected from the group consisting of hydrogen, -C1-C3 alkyl, hydroxy, -C1-C3 alkoxy, cyano, -C1-C2 haloalkyl, -OC1-C2 haloalkyl, and halo; R3 is selected from the group consisting of hydrogen, -C1-C4 alkyl, -C2-C4 haloalkyl, -C2-C4 alkylOH, -C3-C6 cycloalkyl, -CH2C3-C6 cyxloalkyl, -C2-C4 alkyl-O-C1-C4 alkyl, -C(O)C1-C4 alkyl, -C(O)C1-C4 haloalkyl, -CH2-thiazole, phenyl, benzyl, tetrahydrothiopyranyl, and tetrahydropyranyl, wherein the cycloalkyl, tetrahydrothiopyranyl, tetrahydropyranyl and thiazolyl group is optionally substituted with one or two groups independently selected from the group consisting of halo, hydroxy, C1-C2 alkyl, and -C1-C2 haloalkyl; or a pharmaceutically acceptable salt, enantiomer, diastereomer or mixture thereof,, useful in the treating, preventing or ameliorating of symptoms associated with obesity and related diseases.