103546-10-7

Basic information

• Product Name: 3-(2-Nitrophenoxy)propylamine
• Synonyms: 3-(2-Nitrophenoxy)propylamine;3-(2-nitrophenoxy)-1-Propanamine;3-(2-NITROPHENOXY)PROPAN-1-AMINE
• CAS NO: 103546-10-7
• Molecular Formula: C₉H₁₂N₂O₃
• Molecular Weight: 196
• Mol File: 103546-10-7.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 353°C at 760 mmHg
• Flash Point: 167.3°C
• Appearance: /
• Density: 1.211g/cm³
• Vapor Pressure: 3.69E-05mmHg at 25°C
• Refractive Index: 1.558
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 3-(2-Nitrophenoxy)propylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(2-Nitrophenoxy)propylamine(103546-10-7)
• EPA Substance Registry System: 3-(2-Nitrophenoxy)propylamine(103546-10-7)

Safety Data

• Hazardous Substances Data: 103546-10-7(Hazardous Substances Data)

Usage

General Description

3-(2-Nitrophenoxy)propylamine is an organic compound with a chemical formula C9H12N2O3. It is a derivative of amine and contains a propylamine group attached to a nitrophenyl ether. This chemical is used in the synthesis of various pharmaceuticals and is also employed as an intermediate in organic chemistry. It can be used as a starting material in the production of various drugs and is also used in research laboratories for its unique chemical properties. Additionally, it is important to handle this compound with caution as it may pose health hazards if not used properly.

InChI:InChI=1/C9H12N2O3/c10-6-3-7-14-9-5-2-1-4-8(9)11(12)13/h1-2,4-5H,3,6-7,10H2

Upstream product

• 66725-23-3 N-<3-(o-Nitrophenoxy)propyl>phthalimide 
• 88-75-5 2-hydroxynitrobenzene 
• 104147-69-5 1-(3-bromopropoxy)-2-nitrobenzene 

Downstream Products

• 103523-46-2 α-isopropyl-3,4,5-trimethoxy-α-<3-<<3-(2-nitrophenoxy)propyl>amino>propyl>benzeneacetonitrile 
• 103523-50-8 α-isopropyl-3,4,5-trimethoxy-α-<3--N-methylamino>propyl>benzeneacetonitrile 
• 103523-52-0 α-<3--N-methylamino>propyl>-α-isopropyl-3,4,5-trimethoxybenzeneacetonitrile 
• 103523-48-4 α-<3-<<3-(2-aminophenoxy)propyl>amino>propyl>-α-isopropyl-3,4,5-trimethoxybenzeneacetonitrile 

Relevant articles and documents

Selective small molecules blocking HIV-1 tat and coactivator PCAF association

Development of drug resistance from mutations in the targeted viral proteins leads to continuation of viral production by chronically infected cells, contributing to HIV-mediated immune dysfunction. Targeting a host cell protein essential for viral reproduction, rather than a viral protein, may minimize the viral drug resistance problem as observed with HIV protease inhibitors. We report here the development of a novel class of N1-aryl-propane-1,3-diamine compounds using a structure-based approach that selectively inhibit the activity of the bromodomain of the human transcriptional co-activator PCAF, of which association with the HIV trans-activator Tat is essential for transcription and replication of the integrated HIV provirus. Copyright