103548-65-8Relevant articles and documents
Investigation of a convergent route to purpuromycin: Benzofuran formation vs spiroketalization
Waters, Stephen P.,Fennie, Michael W.,Kozlowski, Marisa C.
, p. 3243 - 3246 (2007/10/03)
A mild and efficient [3+2] nitrile oxide/olefin cycloaddition allows coupling of the highly functionalized naphthalene and isocoumarin hemispheres of purpuromycin. A rationale of the inability of advanced keto alcohols to spirocyclize is presented based u
Evaluation of some preparations of trialkoxyphthalic acid derivatives
Parker, Kathlyn A.,Spero, Denice M.,Koziski, Kathleen A.
, p. 183 - 188 (2007/10/02)
Several approaches to trialkoxyphthalic acid derivatives, potential intermediates in a fredericamycin synthesis, were tested. Sequences based on a Diels-Alder/retro Diels-Alder reaction, a cyanide addition to a quinone, an Elbe oxidation, and an amide-directed ortho-lithiation are discussed in terms of length, yields, convenience, and the versatility of the product of each.
STIPITATIC ACID: SYNTHESIS VIA CYCLOPROPANATED QUINONES
Keith, Dennis D.
, p. 5907 - 5910 (2007/10/02)
A new synthesis of stipitatic acid incorporating a cyclopropanated quinone intermediate is reported.