10424-65-4 Usage
Description
Tetramethylammonium hydroxide pentahydrate is a clathrate hydrate that exhibits high proton conductivity and can readily absorb carbon dioxide. It is a promising candidate for various applications, including energy devices, gas separation, and gas storage.
Uses
Used in Industrial Research:
Tetramethylammonium hydroxide pentahydrate is used as an organic base in industrial research for its wide range of applications.
Used in Organic Silicon Products:
In domestic applications, Tetramethylammonium hydroxide pentahydrate is used as a catalyst for synthesizing silicone oil, silicone rubber, and silicone resin, which significantly affects the yield and quality of the products.
Used in Polyester-based Polymers, Textiles, Plastics, Food, Leather, Wood Processing, Electroplating, and Other Microorganisms:
In foreign applications, Tetramethylammonium hydroxide pentahydrate is used in various industries, including polyester-based polymers, textiles, plastics, food, leather, wood processing, electroplating, and other microorganisms.
Used in Advanced Technology Areas:
Tetramethylammonium hydroxide pentahydrate is used as a cleaning agent in integrated circuits and an anisotropic etchant in semiconductor microfabrication technology of the Si-SiO2 interface in advanced technology areas such as printed circuit board manufacturing and microscopic sheets.
Used as Additive in Silicone Rubber, Methyl Silicone Oil, and Polarographic Analysis Reagents:
Tetramethylammonium hydroxide pentahydrate is used as an additive in silicone rubber, methyl silicone oil, and polarographic analysis reagents.
Used as Catalyst in Organosilicone:
In organosilicone, Tetramethylammonium hydroxide pentahydrate is used as a catalyst for dimethyl silicone oil, phenylmethyl silicone oil, a silicone oil diffusion pump, solvent-free silicone molding compound, silicone resin, and silicone rubber.
Used in Polarography and Product Purification:
Tetramethylammonium hydroxide pentahydrate is used as a polarography agent and as a non-gray base to precipitate many metal elements in product purification.
Used in Silicon Computer Face Brightener and Cleaning Agents:
Tetramethylammonium hydroxide pentahydrate is used as a silicon computer face brightener, cleaning agents, and engraved touch in the production of organic silicon.
Used in Study of Pseudomonas Species:
Tetramethylammonium hydroxide pentahydrate has been used in a study to assess strains of Pseudomonas species by a single-step gas chromatographic characterization procedure.
Used in Investigation of Solid-state Metal Hydride Batteries:
Tetramethylammonium hydroxide pentahydrate has been used in a study to investigate solid-state metal hydride batteries, such as nickel oxyhydroxide-metal hydride and manganese dioxide-metal hydride.
Used in Preparation of Gamma-Cesium Lead Iodide Films:
Tetramethylammonium hydroxide pentahydrate is a useful compound for preparing gamma-cesium lead iodide films for high-efficiency deep-red light-emitting devices.
Used in Preparation of Mesoporous Molecular Sieve MCM-41:
Tetramethylammonium hydroxide pentahydrate may be used in the preparation of a mesoporous molecular sieve belonging to the MCM-41 category with silica to (tetrahedral) aluminum ratio as low as 8.5:1.
Outline
Tetramethylammonium hydroxide (TMAH) is the strongest organic base, it is colorless, odorless. Vapor pressure is low at room temperature, it can completely decompose and vaporize at 135~145℃, high purity product has no trace residue by low temperature treatment at 140℃.
Tetramethylammonium hydroxide solution is colorless and transparent with micro smell of ammonia, PH value of 1(wt)% solution is 12.9, it is strong alkali which has equal strength with caustic alkali. The tetramethylammonium hydroxide aqueous solution is concentrated under reduced pressure to obtain five crystal water absorbent needle-like crystals (mp, 63℃), then it continues dewatering into three crystal water of crystallization (mp, 63℃), then it turns into a crystal water of tetramethylammonium hydroxide, at 135~140℃, it can decompose into trimethylamine and dimethyl ether.
preparation methods
It has many preparation methods of tetramethylammonium hydroxide, silver oxide method is commonly used, it is producted by the reaction of tetramethylammonium chloride with silver oxide. However, the preparation method of tetramethylammonium hydroxide is a complex process, the feedstock of silver oxide is expensive, and the resulting product contains higher impurity ions, such as halide ions, alkali metal ions, for the catalytic polymerization of organosilicon monomers, it has severe effect of silicone product features, and it can not meet the requirements for cleaning and corrosion in electronic fields.
From the seventies, foreign began to use new technology of electrolytic method to prepare tetramethylammonium hydroxide, and this method gradually replaced the silver oxide method. Electrolytic method has better product quality, low cost, it not only meets the needs of the production of organic silicon, but also has entered the electronics industry.
The above information is edited by the lookchem of Wang Xiaodong.
Process description of electrolysis
1. Tetramethylammonium chloride as raw material
The principle is that tetramethyl ammonium chloride aqueous solution in the electrolytic cell of anode compartment under the action of the electric force, the chloride ions in solution migrate to the anode and discharge of chlorine deposited on the anode. Meanwhile, since the ion-exchange membrane selective permeability, chloride diffusion can not go through the ion-exchange membrane, only tetramethylammonium ions can select and penetrate, then come into the cathode compartment, and enriched therein. The molecules water in electrolytic cell of cathode compartment can decompose into hydrogen and hydroxyl ions. The latter is exactly combined with tetramethylammonium ions from the anode chamber into tetramethylammonium hydroxide. With the increase of electricity, the concentration of tetramethylammonium hydroxide continues to improve to achieve the desired final concentration of crude.
Anodic electrochemical reaction is:
(CH3) 4NCl → (CH3) 4N ++ Clˉ
2Clˉ-2e → Cl2 ↑
Cathodic electrochemical reaction is:
H2O → H + + OHˉ
(CH3) 4N ++ OHˉ → (CH3) 4NOH
2H ++ 2e → H2 ↑
The overall reaction is: 2 (CH3) 4NCl + 2H2O → 2 (CH3) 4NOH + H2 ↑ + Cl2 ↑
The produced hydrogen of electrolysis is vented, resulting chlorine is absorbed with lye to generate sodium hypochlorite, sodium hypochlorite is the main raw material of bleach. Therefore, this preparation method of tetramethylammonium hydroxide is simple, high purity, and has no environmental pollution.
2.Tetramethyl-ammonium bicarbonate as starting material
The theory of electrolysis is similar with tetramethylammonium chloride as raw material, but chlorine can not generate in this method, carbon dioxide and oxygen generate at the anode. Total reaction: (CH3) 4NHCO3 + H2O (CH3) 4NOH + CO2 ↑ + H2 ↑
Purification Methods
It is freed from chloride ions by passage through an ion-exchange column (e.g. Amberlite IRA-400, prepared in its OH-form by passing 2M NaOH until the effluent is free from chloride ions, then washed with distilled H2O until neutral). A modification, to obtain carbonate-free hydroxide, uses the method of Davies and Nancollas [Nature 165 237 1950]. [Beilstein 4 IV 145.]
Check Digit Verification of cas no
The CAS Registry Mumber 10424-65-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,4,2 and 4 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10424-65:
(7*1)+(6*0)+(5*4)+(4*2)+(3*4)+(2*6)+(1*5)=64
64 % 10 = 4
So 10424-65-4 is a valid CAS Registry Number.
InChI:InChI=1/C4H12N.6H2O/c1-5(2,3)4;;;;;;/h1-4H3;6*1H2/q+1;;;;;;/p-1
10424-65-4Relevant articles and documents
VLA-4 INHIBITOR
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, (2008/06/13)
An object of the present invention is to provide a compound which selectively inhibits binding of a ligand and ±421 integrin (VLA-4), a process for producing the compound, and a medicament containing the compound. A compound represented by the formula (I) etc. orasaltthereof, a process for producing the compound or a salt thereof, a medicament containing the compound or a salt thereof, as well as a preventive and/or a therapeutic agent for a disease caused by cell adhesion, for example, inflammatory reaction, autoimmune disease, cancer metastasis, bronchial asthma, nasal obstruction, diabetes, arthritis, psoriasis, multiple sclerosis, inflammatory bowel disease and rejection reaction at transplantation, containing the compound or a salt thereof as a primary component. [wherein Y 1 represents a divalent aryl group etc. , V 1 represents an aryl group etc., and R 11 to R 14 represent H, OH or a halogen atom etc.]
