105116-40-3Relevant articles and documents
Nonpeptidic lysosomal modulators derived from Z-Phe-Ala-diazomethylketone for treating protein accumulation diseases
Viswanathan, Kishore,Hoover, Dennis J.,Hwang, Jeannie,Wisniewski, Meagan L.,Ikonne, Uzoma S.,Bahr, Ben A.,Wright, Dennis L.
, p. 920 - 924 (2013/01/15)
Lysosomes are involved in protein turnover and removing misfolded species, and their enzymes have the potential to offset the defect in proteolytic clearance that contributes to the age-related dementia Alzheimer's disease (AD). The weak cathepsin B and L