10517-47-2

Basic information

• Product Name: Ethanone, 1-[4-(hydroxyamino)phenyl]-
• Synonyms: Ethanone, 1-[4-(hydroxyamino)phenyl]-
• CAS NO: 10517-47-2
• Molecular Formula: C₈H₉NO₂
• Molecular Weight: 151.16
• Mol File: 10517-47-2.mol
• Article Data: 28

Chemical Properties

• Boiling Point: 314°Cat760mmHg
• Flash Point: 143.7°C
• Appearance: /
• Density: 1.244g/cm³
• Vapor Pressure: 0.000204mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: Ethanone, 1-[4-(hydroxyamino)phenyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-[4-(hydroxyamino)phenyl]-(10517-47-2)
• EPA Substance Registry System: Ethanone, 1-[4-(hydroxyamino)phenyl]-(10517-47-2)

Safety Data

• Hazardous Substances Data: 10517-47-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C8H9NO2/c1-6(10)7-2-4-8(9-11)5-3-7/h2-5,9,11H,1H3

Upstream product

• 99-92-3 p-aminobenzophenone 
• 100-19-6 (4-nitrophenyl)ethanone 
• 31125-05-0 1-(4-nitrosophenyl)ethan-1-one 

Downstream Products

• 99-92-3 p-aminobenzophenone 
• 75-07-0 acetaldehyde 
• 18179-86-7 4,4'-diacetylazobenzene 
• 67274-51-5 N-(4-acetylphenyl)-N-hydroxyacetamide 

Relevant articles and documents

Photochemistry of p-Nitroacetophenone in 2-Propanol

Upon irradiation in 2-propanol, p-nitroacetophenone 1 was reduced via the triplet state to p-hydroxyammoacetophenone 5 which was further reduced top-aminoacetophenone 2 and 4,4′-diacetylazobenzene 4. Similar irradiation of 5 also gave 2 and 4, and its oxidation by oxygen gave 4,4′-diacetylazoxybenzene 3. Photolysis of monomeric p-nitrosoacetophenone 6 afforded acetophenone and 3 that were not produced during the irradiation of 1 Possible photoreaction pathways were discussed on the basis of published mechanisms.

Polystyrene stabilized iridium nanoparticles catalyzed chemo- and regio-selective semi-hydrogenation of nitroarenes to N-arylhydroxylamines

Polystyrene stabilized Iridium (Ir@PS) nanoparticles (NPs) as a heterogeneous catalyst have been developed and characterized by IR, UV–Vis, SEM, TEM, EDX and XRD studies. The prepared Ir@PS catalyst showed excellent reactivity for chemo- and regio-selective controlled-hydrogenation of functionalized nitroarenes to corresponding N-arylhydroxylamine using hydrazine hydrate as reducing source and environmentally benign polyethylene glycol (PEG-400) as green solvent. The present methodology was applied for vast substrate scope and found to be compatible with wide range of reducible functional groups. The reaction performed at 85 °C or ambient temperature and completed within 5–80 minutes. The catalyst can easily be filtered out from reaction mixture and reusable.

Catalyst-Free N-Deoxygenation by Photoexcitation of Hantzsch Ester

A mild and operationally simple protocol for the deoxygenation of a variety of heteroaryl N-oxides and nitroarenes has been developed. A mixture of substrate and Hantzsch ester is proposed to result in an electron donor-acceptor complex, which upon blue-light irradiation undergoes photoinduced electron transfer between the two reactants to afford the products. N-oxide deoxygenation is demonstrated with 22 examples of functionally diverse substrates, and the chemoselective reduction of nitroarenes to the corresponding hydroxylamines is also shown.