106119-62-4

Basic information

• Product Name: 4-Pyrimidinamine, N-hydroxy-2,6-diphenyl-
• CAS NO: 106119-62-4
• Molecular Formula: C16H13N3O
• Molecular Weight: 263.299
• Mol File: 106119-62-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-Pyrimidinamine, N-hydroxy-2,6-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Pyrimidinamine, N-hydroxy-2,6-diphenyl-(106119-62-4)
• EPA Substance Registry System: 4-Pyrimidinamine, N-hydroxy-2,6-diphenyl-(106119-62-4)

Safety Data

• Hazardous Substances Data: 106119-62-4(Hazardous Substances Data)

Upstream product

• 29509-91-9 4-chloro-2,6-diphenyl-1,3-pyrimidine 
• 126382-49-8 4-Nitroso-2,6-diphenylpyrimidine 

Downstream Products

• 126382-63-6 2,2',4,4'-tetraphenyl-6,6'-azoxypyrimidine 
• 106119-63-5 4-nitro-2,6-diphenylpyrimidine 
• 126382-49-8 4-Nitroso-2,6-diphenylpyrimidine 
• 15969-46-7 2,6-diphenylpyrimidin-4-ol 
• 60545-99-5 2-Methoxy-4,6-dimethylpyrimidin 
• 126382-64-7 4-Methoxy-2,6-dimethylpyrimidin 
• 126382-55-6 (2,6-Diphenyl-pyrimidin-4-yl)-phenyl-diazene 
• 15969-46-7 2,6-diphenyl-3H-pyrimidin-4-one 
• 120819-10-5 C₂₆H₂₂N₄O₄ 
• 120818-96-4 2-Chloro-N-(2,6-diphenyl-pyrimidin-4-yl)-N-hydroxy-acetamide 
• 120819-08-1 C₂₁H₂₂N₄O₂ 
• 120819-09-2 C₂₃H₁₆Cl₂N₄O₂ 
• 120836-28-4 2-Chloro-N-(2-chloro-acetoxy)-N-(2,6-diphenyl-pyrimidin-4-yl)-acetamide 
• 120818-89-5 4-(N-acetyl-N-acetyloxy)amino-2,6-diphenylpyrimidine 

Relevant articles and documents

Catalytic Enantioselective Nitroso Diels-Alder Reaction

The nitroso Diels-Alder (NDA) reaction is an attractive strategy for the synthesis of 3,6-dihydro-1,2-oxazines and 1-amino-4-hydroxy-2-ene derivatives. Herein we report the Cu(I)-DTBM-Segphos catalyzed asymmetric intermolecular NDA reaction of variously substituted cyclic 1,3-dienes using highly reactive nitroso compounds derived from pyrimidine and pyridazine derivatives. In most of the cases studied, the cycloadducts were obtained in high yields (up to 99%) with very high regio-, diastereo-, and enantioselectivities (up to regioselectivity > 99:1, d.r. > 99:1, and >99% ee). As an application of this methodology, formal syntheses of conduramine A-1 and narciclasine were accomplished.

SYNTHESIS OF SUBSTITUTED 2- AND 4-HYDROXYAMINOPYRIMIDINES

The reaction of 2- and 4-chlorine-containing alkyl(aryl)pyrimidines with hydroxylamine was studied.It was shown that, depending on the amount of hydroxylamine , N,O-dipyrimidinylhydroxyamides or the corresponding 2- and 4-hydroxyaminopyrimidines are formed together with 2- and 4-oxodihydropyrimidines.