1061743-02-9Relevant articles and documents
Diagnostic agents selective against metalloproteases
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, (2016/11/21)
The invention relates to aryl-sulphonamido compounds endowed with affinity against metallo proteases MMP, having formula (I) below wherein R, R1, R2, R3, G and n have the meanings reported in the specification, properly la
ARYL-SULPHONAMIDIC DIMERS AS METALLOPROTEASES INHIBITORS
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Page/Page column 18; 24; 37, (2010/03/02)
The invention relates to dimeric aryl-sulphonamido compounds endowed with inhibitory activity against metalloproteases MMP, having formula (I) below ???????? (M)-L-(M')?????(I) wherein M and M', the same or different from each other, represent the residues of the mctalloprotcascs inhibitors of formula (II) wherein R, R1, R2, R3, G and n have the meanings reported in the specification; the invention also refers to the process for their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of degenerative disorders.