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110-25-8

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110-25-8 Usage

Description

N-OLEOYLSARCOSINE, also known as 2-(N-Methyloleamido)acetic acid, is a light yellow liquid with unique chemical properties. It is a derivative of sarcosine, an amino acid, and oleic acid, a fatty acid. Its molecular structure allows it to form complexes with various substances, making it a versatile compound in different industries.

Uses

Used in Lubricating Oil and Grease Industry:
N-OLEOYLSARCOSINE is used as an anti-tarnishing sunscreen additive for lubricating oil and grease. Its ability to form complexes with metal ions helps prevent the oxidation and corrosion of metal surfaces, thereby extending the life of the lubricants and protecting the machinery from wear and tear.
Used in Cosmetics Industry:
N-OLEOYLSARCOSINE is used as an emulsifier and solubilizer in cosmetic formulations. Its amphiphilic nature allows it to mix oil and water-based ingredients, creating stable emulsions. It also helps improve the texture and spreadability of the products, providing a smooth and non-greasy feel on the skin.
Used in Pharmaceutical Industry:
N-OLEOYLSARCOSINE is used as a penetration enhancer in transdermal drug delivery systems. Its ability to interact with the skin's lipids and proteins enables the efficient delivery of drugs through the skin, improving the bioavailability and therapeutic effects of the medication.
Used in Food Industry:
N-OLEOYLSARCOSINE is used as a flavor enhancer and emulsifier in the food industry. Its ability to bind with taste receptors and improve the stability of food emulsions contributes to the enhancement of flavor and texture in various food products.

Check Digit Verification of cas no

The CAS Registry Mumber 110-25-8 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,1 and 0 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 110-25:
(5*1)+(4*1)+(3*0)+(2*2)+(1*5)=18
18 % 10 = 8
So 110-25-8 is a valid CAS Registry Number.
InChI:InChI=1/C21H39NO3/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-20(23)22(2)19-21(24)25/h10-11H,3-9,12-19H2,1-2H3,(H,24,25)/b11-10-

110-25-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(N-Methyloleamido)acetic acid

1.2 Other means of identification

Product number -
Other names N-OLEOYLSARCOSINE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Corrosion inhibitors and anti-scaling agents
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:110-25-8 SDS

110-25-8Synthetic route

N-oleoylsarcosine methyl ester

N-oleoylsarcosine methyl ester

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

Conditions
ConditionsYield
Stage #1: N-oleoylsarcosine methyl ester With lithium hydroxide In ethanol; water at 20℃; for 12h;
Stage #2: With hydrogenchloride In water pH=2;
98%
sodium sarcosinate
4316-73-8

sodium sarcosinate

oleic acid chloride

oleic acid chloride

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

Conditions
ConditionsYield
With water; sodium hydroxide In toluene at 30℃; for 1h; Solvent;97.8%
(Z)-9-octadecenoyl chloride
112-77-6

(Z)-9-octadecenoyl chloride

sarcosine
107-97-1

sarcosine

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

Conditions
ConditionsYield
With sodium hydroxide
sarcosine
107-97-1

sarcosine

cis-Octadecenoic acid
112-80-1

cis-Octadecenoic acid

sodium sarcosinate
4316-73-8

sodium sarcosinate

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

Conditions
ConditionsYield
In water; isopropyl alcohol
(Z)-9-octadecenoyl chloride
112-77-6

(Z)-9-octadecenoyl chloride

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane; methanol / 0 - 20 °C
2.1: lithium hydroxide / ethanol; water / 12 h / 20 °C
2.2: pH 2
View Scheme
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

6-nitroveratryl alcohol
1016-58-6

6-nitroveratryl alcohol

4,5-dimethoxy-2-nitrobenzyl [methyl(oleoyl)amino]acetate
1413644-53-7

4,5-dimethoxy-2-nitrobenzyl [methyl(oleoyl)amino]acetate

Conditions
ConditionsYield
Stage #1: N-oleoylsarcosine With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; Inert atmosphere;
Stage #2: 6-nitroveratryl alcohol In dichloromethane at 20℃; Inert atmosphere;
82%
2-Ethylhexyl alcohol
104-76-7

2-Ethylhexyl alcohol

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

2-ethylhexyl N-oleoylsarcosinate

2-ethylhexyl N-oleoylsarcosinate

Conditions
ConditionsYield
at 150℃; for 3h; Inert atmosphere; Dean-Stark;
at 150℃; for 3h; Dean-Stark; Inert atmosphere;421.7 g
at 150℃; for 3h; Dean-Stark; Inert atmosphere;421.7 g
at 150℃; for 3h; Dean-Stark; Inert atmosphere; Reflux;421.7 g
2-Ethylhexylamine
104-75-6

2-Ethylhexylamine

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

N'-2-ethylhexyl N-oleoylsarcosinamide

N'-2-ethylhexyl N-oleoylsarcosinamide

Conditions
ConditionsYield
at 130℃; for 3h; Inert atmosphere; Dean-Stark;
at 130℃; for 3h; Dean-Stark; Inert atmosphere;266.6 g
at 130℃; for 3h; Dean-Stark; Inert atmosphere;266.6 g
at 130℃; for 3h; Dean-Stark; Inert atmosphere;266.6 g
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

2,2'-iminobis[ethanol]
111-42-2

2,2'-iminobis[ethanol]

N',N' bis(2-hydroxyethyl) N-oleoylsarcosinamide

N',N' bis(2-hydroxyethyl) N-oleoylsarcosinamide

Conditions
ConditionsYield
With Amberlyst 15 acidic resin at 150℃; for 3h; Inert atmosphere; Dean-Stark;
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;371.6 g
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;371.6 g
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;371.6 g
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

butan-1-ol
71-36-3

butan-1-ol

butyl N-oleoylsarcosinate

butyl N-oleoylsarcosinate

Conditions
ConditionsYield
With Amberlyst 15 acidic resin for 3h; Inert atmosphere; Dean-Stark; Reflux;310 g
With Amberlyst 15 acidic resin for 3h; Dean-Stark; Reflux; Inert atmosphere;310 g
With Amberlyst 15 acidic resin for 3h; Dean-Stark; Inert atmosphere; Reflux;310 g
With Amberlyst 15 acidic resin for 3h; Dean-Stark; Inert atmosphere; Reflux;310 g
ethanol
64-17-5

ethanol

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

ethyl N-oleoylsarcosinate

ethyl N-oleoylsarcosinate

Conditions
ConditionsYield
for 3h; Inert atmosphere; Dean-Stark; Reflux;280 g
for 3h; Dean-Stark; Inert atmosphere; Reflux;280 g
for 3h; Dean-Stark; Inert atmosphere; Reflux;280 g
for 3h; Dean-Stark; Inert atmosphere; Reflux;280 g
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

2-methoxyethyl N-oleoylsarcosinate

2-methoxyethyl N-oleoylsarcosinate

Conditions
ConditionsYield
With Amberlyst 15 acidic resin at 160℃; for 3h; Inert atmosphere; Dean-Stark;
With Amberlyst 15 acidic resin at 160℃; for 3h; Dean-Stark; Inert atmosphere;273.5 g
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

ethylene glycol
107-21-1

ethylene glycol

2-hydroxyethyl N-oleoylsarcosinate

2-hydroxyethyl N-oleoylsarcosinate

Conditions
ConditionsYield
With Amberlyst 15 acidic resin at 160℃; for 3h; Inert atmosphere; Dean-Stark;
With Amberlyst 15 acidic resin at 160℃; for 3h; Dean-Stark; Inert atmosphere;312.7 g
With Amberlyst 15 acidic resin at 160℃; for 3h; Dean-Stark; Inert atmosphere;312.7 g
With Amberlyst 15 acidic resin at 160℃; for 3h; Dean-Stark; Inert atmosphere;312.7 g
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

2-methoxyethylamine
109-85-3

2-methoxyethylamine

N'-2-methoxyethyl N-oleoylsarcosinamide

N'-2-methoxyethyl N-oleoylsarcosinamide

Conditions
ConditionsYield
With Amberlyst 15 acidic resin at 150℃; for 3h; Inert atmosphere; Dean-Stark;
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;263.9 g
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;263.9 g
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark;263.9 g
N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

1-amino-3-(dimethylamino)propane
109-55-7

1-amino-3-(dimethylamino)propane

N-oleoyl-N'-3-(dimethylamino)propylsarcosinamide

N-oleoyl-N'-3-(dimethylamino)propylsarcosinamide

Conditions
ConditionsYield
With Amberlyst 15 acidic resin at 150℃; for 3h; Inert atmosphere; Dean-Stark;
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;377.8 g
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;377.8 g
With Amberlyst 15 acidic resin at 150℃; for 3h; Dean-Stark; Inert atmosphere;377.8 g
2-(2-methoxyethoxy)ethyl alcohol
111-77-3

2-(2-methoxyethoxy)ethyl alcohol

N-oleoylsarcosine
110-25-8

N-oleoylsarcosine

2-methoxyethyl N-oleoylsarcosinate

2-methoxyethyl N-oleoylsarcosinate

Conditions
ConditionsYield
With Amberlyst 15 acidic resin at 160℃; for 3h; Dean-Stark; Inert atmosphere;273.5 g
With Amberlyst 15 acidic resin at 160℃; for 3h; Dean-Stark; Inert atmosphere;273.5 g

110-25-8Relevant articles and documents

PRODUCTION PROCESS FOR N-ACYLAMINO ACID

-

Paragraph 0028, (2017/06/09)

PROBLEM TO BE SOLVED: To provide a production process in which a high-purity N-acylamino acid having a good color tone can be produced with high yield. SOLUTION: A production process for N-acylamino acid is provided in which an acylation reaction between an amino acid represented by formula (1) and a fatty acid chloride having a carbon number of 16 to 22 is performed in a mixed solvent between a water and an organic solvent and having an octanol/water partition coefficient of 1.6 to 3.5 under an alkali condition. (In the formula (1), R1 represents a hydrogen atom or a methyl group, R2 represents a hydrogen atom or an alkali metal atom, and n represents an integer of 1 or 2.). SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

Preparation of alkali metal acyl amino acids

-

, (2008/06/13)

A process of preparing alkali metal N-acyl amino acids, especially sodium N-acyl sarcosinates. The process of the invention eliminates the use of phosphorus trichloride or thionyl chloride and carboxylic acid chlorides. The process involves reacting the alkali metal N-acyl amino acid directly with a fatty acid at elevated temperatures with constant removal of water generated in the reaction.

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