110814-90-9

Basic information

• Product Name: 2H-Pyrido[1,2-a]pyrazine-6-carbonitrile,hexahydro-1-oxo-,cis-(9CI)
• Synonyms: 2H-Pyrido[1,2-a]pyrazine-6-carbonitrile,hexahydro-1-oxo-,cis-(9CI);(6R,9AR)-1-OXOOCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZINE-6-CARBONITRILE
• CAS NO: 110814-90-9
• Molecular Formula: C9 H13 N3 O
• Molecular Weight: 179.22
• Product Categories: PIPERIDINE
• Mol File: 110814-90-9.mol
• Article Data: 1

Chemical Properties

• Melting Point: 117-118 °C
• Boiling Point: 435.9±40.0 °C(Predicted)
• Appearance: /
• Density: 1.22±0.1 g/cm3(Predicted)
• PKA: 14.71±0.40(Predicted)
• CAS DataBase Reference: 2H-Pyrido[1,2-a]pyrazine-6-carbonitrile,hexahydro-1-oxo-,cis-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-Pyrido[1,2-a]pyrazine-6-carbonitrile,hexahydro-1-oxo-,cis-(9CI)(110814-90-9)
• EPA Substance Registry System: 2H-Pyrido[1,2-a]pyrazine-6-carbonitrile,hexahydro-1-oxo-,cis-(9CI)(110814-90-9)

Safety Data

• Hazardous Substances Data: 110814-90-9(Hazardous Substances Data)

Upstream product

• 151-50-8 potassium cyanide 
• 107-15-3 ethylenediamine 
• 111-30-8 Glutaraldehyde 

Relevant articles and documents

NEW SAYNTHESES OF 1-AMINO- AND 1-(2-AMINOETHYL)-2,6-DICYANOPIPERIDINES AND DIAZABICYCLO COMPOUNDS BY A STRECKER REACTION USING GLUTARALDEHYDE AND DIAMINES, AND THEIR STEREOCHEMISTRY

An efficient sequence proposed here involves a simple Strecker reaction of glutaraldehyde with hydrazine or 1,2-diaminoethane, which gives 1-amino- or 1-(2-aminoethyl)2,6-dicyanopiperidines, 2-cyano-1,7-diazabicyclononane, and 10-cyano-1,4-diazabicyclodecan-5-one.Their stereochemistry is also elucidated.Moreover, treatment of 1-amino-2,6-dicyanopiperidine and phthaloyl dichloride in the presence of 4-(N,N-dimethylamino)pyridine quantitatively gives 1-phthalimido-2,6-dicyanopiperidine.