1116-24-1Relevant articles and documents
Solute-Solute Interactions in Non-aqueous Solvents. Enthalpic Interaction Coefficients of Substituted Acetamides Dissolved in N,N-Dimethylformamide
Bloemendal, M.,Somsen, G.
, p. 83 - 100 (1983)
Enthalpies of dilution of acetamide, N-methylacetamide, N-ethylacetamide, N-propylacetamide, N-butylacetamide, N,N-dimethylacetamide, N,N-diethylacetamide, N,N-dipropylacetamide and N,N-dibutylacetamide dissolved in N,N-dimethyacetamide as solvent have been measured calorimetrically at 25 deg C.The results are interpreted in terms of McMillan-Mayer theory.The enthalpic interaction parameters are obtained for pairs, triplets and some quadruplets of solute molecules.All enthalpic pair interaction coefficients but one in this nonaqueous solvent are negative, whereas the triplet coefficients are positive.The concept of "solvophobic interaction" can be used to explain these results in connection with the assumption of the formation of solute-solvent associates.The enthalpic pair interaction coefficients can be described by the additivity approach of Savage and Wood.
Visible Light-Driven, One-pot Amide Synthesis Catalyzed by the B12 Model Complex under Aerobic Conditions
Tian, Hui,Shimakoshi, Hisashi,Ono, Toshikazu,Hisaeda, Yoshio
, p. 237 - 240 (2018/12/13)
A visible light responsive catalytic system with the B12 complex as the catalyst and [Ir(dtbbpy)(ppy)2]PF6 as the photosensitizer was developed. It provides a convenient and efficient way to synthesize amides. Based on this method, trichlorinated organic compounds were converted into amides in the presence of an amine under aerobic conditions at room temperature in a one-pot procedure. Various trichlorinated organic compounds and an amine source, such as primary, secondary, and cyclic amines, have been evaluated for this transformation, providing the expected products in moderate to excellent yields. Notably, product formation depended on the reaction atmosphere where the amide was obtained under aerobic conditions while partially dechlorinated products were obtained under anaerobic conditions. As this protocol is free from hazardous reagents, extra additives, noble metals, and dangerous gas, the present method provides a novel and efficient approach for amide synthesis under mild and easily controlled conditions.
Efficient one-pot synthesis of N-substituted 2-aminochromones, their benzo-fused derivatives, and diaminobenzodipyrandiones of two new structural classes
Roma, Giorgio,Piras, Daniela,Di Braccio, Mario,Grossi, Giancarlo
experimental part, p. 849 - 857 (2010/10/02)
N-Substituted 2-aminochromones and their benzo-fused derivatives were obtained in high yields by a new one-pot synthesis, starting from the appropriate acetamides, salicylic acid or its benzo-fused derivatives, and phosphoryl chloride. By the same reaction, from suitable dihydroxybenzenedicarboxylic acids, some compounds of two new structural classes, 2,7-diaminobenzo[1,2-b:4,5-b']dipyran-4,9-diones and 2,8-diamino-4H,6H-benzo[1,2-b:5,4-b']dipyran-4,6-diones, were synthesized. Georg Thieme Verlag Stuttgart.
