1129-30-2Relevant articles and documents
Controlled synthesis of 2-acetyl-6-carbethoxypyridine and 2,6-diacetylpyridine from 2,6-dimethylpyridine
Su, Biyun,Zhao, Jianshe,Cui, Yong,Liang, Yongqing,Sun, Wenhua
, p. 2317 - 2324 (2005)
The controlled syntheses of mono- and bis-acetylpyridine from the same starting material (2,6-dimethylpyridine) are reported, including the asymmetrical compound 2-acetyl-6-carbethoxypyridine, which has not before been reported. The influences of the amount of catalyst EtONa and the reaction conditions to the final products are also explored. A modification of the reported preparation for the 2,6-dipicolinic acid, 2,6-dicarbethoxypyridine and 2,6-diacetylpyridine with higher purity and improved yields is provided here, and the physical and spectral properties of these products are identical to those reported in the literature. Copyright Taylor & Francis, Inc.
Copper ion fluorescence sensor molecules, preparation method, and application in detection of copper ions
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Page/Page column 7, (2019/08/26)
The invention discloses copper ion fluorescence sensor molecules, a preparation method, and application in detection of copper ions. The molecular chemical formula of a sensor is C29H35N7O4, and has the structure which is as shown in formula I; the preparation method of the copper ion fluorescence sensor molecules comprises the steps of taking 2,6-pyridinedicarboxylic acid as a raw material, chloridizing, performing hydrazinolysis and performing condensation reaction to obtain the sensor molecules. The prepared sensor molecules have high selectivity and sensitivity to the copper ions in a DMSOsolution, have obvious visual colorimetric response, and moreover, are not interfered with other cations. According to the preparation method, ion detection paper which is loaded with the sensor molecules is prepared and has the advantages of convenience in carrying, obvious phenomenon, rapid detection and the like. In addition, the fluorescence sensor molecules prepared by the preparation methodis simple in synthesis method and low in cost, and has a very good application prospect in the field of cationic detection.
Organopromoted Selectivity-Switchable Synthesis of Polyketones
Liu, Jie,Hu, Kang-Fei,Qu, Jian-Ping,Kang, Yan-Biao
supporting information, p. 5593 - 5596 (2017/10/25)
In this work, an organopromoted metal-free pharmaceutical-oriented selectivity-switchable benzylic oxidation was developed, affording mono-, di-, and trioxygenation products, respectively, using oxygen as the oxidant under mild conditions. This process facilitates dioxygenation of 2,6-benzylic positions of heterocycles, which could be inhibited by heterocycle chelation to the metal cocatalysts. Enantiopure chiral ketones could also be prepared. The noninvolvement of transition metals and toxins avoids metal or hazardous residues, consequently ensuring a final-stage gram-scale synthesis of Lenperone.
