1133970-57-6

Basic information

• Product Name: (2S)-1-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)-2-(hydroxymethyl)pyrrolidine
• Synonyms: (2S)-1-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)-2-(hydroxymethyl)pyrrolidine
• CAS NO: 1133970-57-6
• Molecular Weight: 321.419
• Mol File: 1133970-57-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2S)-1-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)-2-(hydroxymethyl)pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)-2-(hydroxymethyl)pyrrolidine(1133970-57-6)
• EPA Substance Registry System: (2S)-1-(1-(4-methoxyphenyl)-3-phenylprop-2-yn-1-yl)-2-(hydroxymethyl)pyrrolidine(1133970-57-6)

Safety Data

• Hazardous Substances Data: 1133970-57-6(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 536-74-3 phenylacetylene 
• 23356-96-9 (S)-1-Pyrrolidin-2-yl-methanol 

Relevant articles and documents

Diastereoselective synthesis of propargylamines catalyzed by Cu-MCM-41

In this work, a rapid, efficient and protecting group free diastereoselective synthesis of propargylamines through a multicomponent coupling reaction between (S)-prolinol, phenylacetylene and commercially available aldehydes catalyzed by Cu-MCM-41 in hete

Gold(III) (C^N) complex-catalyzed synthesis of propargylamines via a three-component coupling reaction of aldehydes, amines and alkynes

Propargylamines are synthesized in high yields via a gold(III) (C^N) complex-catalyzed three-component coupling reaction of aldehydes, amines and alkynes in water at 40 °C. Excellent diastereoselectivities (up to 99:1) have been achieved when chiral prolinol derivatives are employed as the amine component. Notably, the [Au(C^N)Cl2] complex (N^CH = 2-phenylpyridine) could be repeatedly used for 10 reaction cycles, leading to an overall turnover number of 812.