1151854-04-4

Basic information

• Product Name: tert-butyl Nα-[(fluoren-9-yl)methoxylcarbonyl]-L-tyrosine trichloroethyl sulfate
• Synonyms: tert-butyl Nα-[(fluoren-9-yl)methoxylcarbonyl]-L-tyrosine trichloroethyl sulfate
• CAS NO: 1151854-04-4
• Molecular Weight: 670.995
• Mol File: 1151854-04-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl Nα-[(fluoren-9-yl)methoxylcarbonyl]-L-tyrosine trichloroethyl sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl Nα-[(fluoren-9-yl)methoxylcarbonyl]-L-tyrosine trichloroethyl sulfate(1151854-04-4)
• EPA Substance Registry System: tert-butyl Nα-[(fluoren-9-yl)methoxylcarbonyl]-L-tyrosine trichloroethyl sulfate(1151854-04-4)

Safety Data

• Hazardous Substances Data: 1151854-04-4(Hazardous Substances Data)

Upstream product

• 764-09-0 chlorosulfuric acid 2,2,2-trichloroethyl ester 
• 133852-23-0 tert-butyl (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoate 

Downstream Products

• 1151854-08-8 Nα-[(fluoren-9-yl)methoxylcarbonyl]-L-tyrosine trichloroethyl sulfate 

Relevant articles and documents

Efficient solid-phase synthesis of sulfotyrosine peptides using a sulfate protecting-group strategy

(Chemical Equation Presented) Double protection: Efficient Fmoc-based solid-phase synthesis (SPPS) of sulfotyrosine (sY) peptides is achieved by incorporating the sY residue(s) as a dichlorovinyl-protected (DCV) sulfodiester(s) and using 2-methylpiperidine for Fmoc removal. After removal of the other protecting groups, the DCV group could be cleaved by mild hydrogenolysis giving the sY peptides in good yield.