117646-10-3

Basic information

• Product Name: 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-
• Synonyms: 5-(2,5-dimethoxybenzylidene)-2,2-dimethyl-1,3-dioxane-4,6-dione;5-(2,5-Dimethoxy-benzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione;5-(2,5-dimethoxybenzylidene)-2,2-dimethyl-[1,3]dioxane-4,6-dione
• CAS NO: 117646-10-3
• Molecular Formula: C15H16O6
• Molecular Weight: 292.288
• Mol File: 117646-10-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-(117646-10-3)
• EPA Substance Registry System: 1,3-Dioxane-4,6-dione, 5-[(2,5-dimethoxyphenyl)methylene]-2,2-dimethyl-(117646-10-3)

Safety Data

• Hazardous Substances Data: 117646-10-3(Hazardous Substances Data)

Upstream product

• 2033-24-1 cycl-isopropylidene malonate 
• 93-02-7 2,5-dimethoxybenzaldehyde 
• 59-48-3 2-oxoindole 

Downstream Products

• 93-02-7 2,5-dimethoxybenzaldehyde 
• 15804-86-1 (2E)-ethyl 3-(2,5-dimethoxyphenyl)propenoate 
• 38489-74-6 trans-2,5-dimethoxycinnamic acid 
• 903636-48-6 bis-(2,5-dimethoxy-benzylidene)-hydrazine 
• 1310812-23-7 C₁₂H₁₆N₂O₅ 
• 1310812-18-0 C₁₂H₁₅NO₅ 
• 848610-51-5 5-(2,5-dimethoxybenzyl)-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 697241-77-3 4-(2,5-dimethoxyphenyl)-3,4-dihydropyrano[3,2-c]chromene-2,5-dione 
• 1313876-97-9 C₁₇H₁₆O₆ 
• 1313876-94-6 C₁₈H₂₀O₅ 
• 33538-88-4 3-(2',5'-dimethoxyphenyl)propanal 
• 35924-44-8 6-methoxycoumarin-3-carboxylic acid 

Relevant articles and documents

A transition metal free expedient approach for the C[dbnd]C bond cleavage of arylidene Meldrum's acid and malononitrile derivatives

A transition metal free expedient approach for the C[dbnd]C bond cleavage of electron deficient alkenes such as arylidene Meldrum's acid and malononitrile derivatives are discussed. The C[dbnd]C bond of these compound were cleaved to benzoic acid in good yield at high temperature. Most importantly, with oxone in CH3CN/H2O at 45 °C or m-CPBA in DCM or NaClO2 in THF/H2O or PIDA in THF at room temperature furnished benzaldehyde derivatives selectively in excellent yields.

Nickel nanoparticles catalyzed chemoselective Knoevenagel condensation of Meldrum's acid and tandem enol lactonizations via cascade cyclization sequence

A novel protocol has been reported wherein, polyethylene glycol (PEG) stabilized nickel nanoparticles have been used as catalyst for chemoselective Knoevenagel condensation of aromatic aldehydes and Meldrum's acid to give 5-arylidene Meldrum's acid which underwent tandem enol lactonization by Michael addition/cyclization sequence with active methylene compounds in the presence of Ni nanoparticles to give corresponding enol lactone derivatives.

Synthesis and biological evaluation of arylidene analogues of Meldrum's acid as a new class of antimalarial and antioxidant agents

A series of arylidene analogues of Meldrum's acid were synthesized and evaluated for in vitro antimalarial and antioxidant activities for the first time. The influence of various physico-chemical parameters such as dielectric constant (), donor number (DN