118609-65-7 Usage
Description
(+)-1-(9-FLUORENYL)ETHYL CHLOROFORMATE is a chemical compound with the molecular formula C16H11ClO2. It is an organic compound that is commonly used as a reagent in organic synthesis. This chemical is a chloroformate ester, which means it reacts readily with nucleophiles to form esters and carbamates.
Used in Pharmaceutical Industry:
(+)-1-(9-FLUORENYL)ETHYL CHLOROFORMATE is used as a reagent for the synthesis of pharmaceuticals. Its ability to react with nucleophiles makes it a valuable component in the creation of various drug molecules.
Used in Agrochemical Industry:
(+)-1-(9-FLUORENYL)ETHYL CHLOROFORMATE is used as a reagent for the synthesis of agrochemicals. It aids in the production of various agricultural chemicals that are essential for crop protection and enhancement.
Used in Fine Chemicals Industry:
(+)-1-(9-FLUORENYL)ETHYL CHLOROFORMATE is used as a reagent for the synthesis of other fine chemicals. Its versatility in organic synthesis allows it to be employed in the production of a wide range of specialty chemicals.
It is important to handle (+)-1-(9-FLUORENYL)ETHYL CHLOROFORMATE with caution, as it is a hazardous chemical that can cause skin and eye irritation, and is harmful if ingested or inhaled. Proper safety precautions should be taken when handling and using this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 118609-65-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,1,8,6,0 and 9 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 118609-65:
(8*1)+(7*1)+(6*8)+(5*6)+(4*0)+(3*9)+(2*6)+(1*5)=137
137 % 10 = 7
So 118609-65-7 is a valid CAS Registry Number.
118609-65-7Relevant articles and documents
(S)-(?)-Fluorenylethylchloroformate (FLEC); preparation using asymmetric transfer hydrogenation and application to the analysis and resolution of amines
Amin, Mohammad A.,Camerino, Michelle A.,Mountford, Simon J.,Ma, Xiao,Manallack, David T.,Chalmers, David K.,Wills, Martin,Thompson, Philip E.
, (2019/09/19)
Fluorenylethylchoroformate (FLEC) is a valuable chiral derivatisation reagent that is used for the resolution of a wide variety of chiral amines. Herein, we describe an improved preparation of (S)-(?)-FLEC using an efficient asymmetric catalytic transfer hydrogenation as the key step. We also demonstrate the application of FLEC as a chiral Fmoc equivalent for chiral resolution, with facile deprotection, of tetrahydroquinaldines, and its capacity for inducing regioselective outcomes in nitration reactions.
(+)-Fluorenylethylchloroformate (FLEC)-improved synthesis for application in chiral analysis and peptidomimetic synthesis
Camerino, Michelle A.,Chalmers, David K.,Thompson, Philip E.
, p. 2571 - 2573 (2013/06/05)
An efficient synthesis of the enantiomers of fluorenylethylchloroformate (FLEC) has been achieved that allows the routine application of the reagent for the resolution of chiral amines including unusual amino acids. The utility of the fluorenylethoxycarbonyl (Feoc) group as a chiral Fmoc equivalent, for combined resolution and protection of amino acids, in solid phase peptide synthesis is also shown.