1187525-03-6 Usage
Description
(Z)-4,4,5,5-tetramethyl-2-(2-phenylprop-1-en-1-yl)-1,3,2-dioxaborolane is a boronic acid derivative used in organic synthesis as a reagent for the preparation of boron-containing compounds. It plays a crucial role in the Suzuki-Miyaura coupling reaction, a method widely employed for the formation of carbon-carbon bonds.
Uses
Used in Pharmaceutical Industry:
(Z)-4,4,5,5-tetramethyl-2-(2-phenylprop-1-en-1-yl)-1,3,2-dioxaborolane is used as a synthetic reagent for the development of complex molecules, which are essential in the creation of new drugs and pharmaceutical products. Its ability to form carbon-carbon bonds through the Suzuki-Miyaura coupling reaction makes it a valuable tool in the synthesis of various medicinal compounds.
Used in Agrochemical Industry:
In the agrochemical industry, (Z)-4,4,5,5-tetramethyl-2-(2-phenylprop-1-en-1-yl)-1,3,2-dioxaborolane is used as a synthetic reagent for the synthesis of complex molecules that are vital in the development of new agrochemicals, such as pesticides and fertilizers. Its role in the formation of carbon-carbon bonds is crucial for creating effective and targeted agrochemical products.
Used in Advanced Materials Production:
(Z)-4,4,5,5-tetramethyl-2-(2-phenylprop-1-en-1-yl)-1,3,2-dioxaborolane is used as a synthetic reagent in the production of advanced materials and fine chemicals. Its ability to form carbon-carbon bonds is essential for creating materials with specific properties and applications, such as in electronics, energy storage, and other high-tech industries.
Used in Fine Chemicals Industry:
In the fine chemicals industry, (Z)-4,4,5,5-tetramethyl-2-(2-phenylprop-1-en-1-yl)-1,3,2-dioxaborolane is used as a synthetic reagent for the preparation of boron-containing compounds with specific properties. These compounds are often used in the synthesis of fragrances, dyes, and other specialty chemicals that require precise molecular structures.
Check Digit Verification of cas no
The CAS Registry Mumber 1187525-03-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,5,2 and 5 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1187525-03:
(9*1)+(8*1)+(7*8)+(6*7)+(5*5)+(4*2)+(3*5)+(2*0)+(1*3)=166
166 % 10 = 6
So 1187525-03-6 is a valid CAS Registry Number.
1187525-03-6Relevant articles and documents
Direct synthesis of alkenyl boronic esters from unfunctionalized alkenes: A boryl-heck reaction
Reid, William B.,Spillane, Jesse J.,Krause, Sarah B.,Watson, Donald A.
, p. 5539 - 5542 (2016)
We report the first example of a boryl-Heck reaction using an electrophilic boron reagent. This palladium-catalyzed process allows for the conversion of terminal alkenes to trans-alkenyl boronic esters using commercially available catecholchloroborane (catBCl). In situ transesterification allows for rapid access to a variety of boronic esters, amides, and other alkenyl boron adducts.
Rh-Catalyzed Asymmetric Hydrogenation of α,β- and β,β-Disubstituted Unsaturated Boronate Esters
Hou, Guohua,Shen, Xin,Yan, Qiaozhi,Zi, Guofu
, (2020/05/08)
A highly enantioselective hydrogenation of α,β-unsaturated boronate esters catalyzed by Rh-(S)-DTBM-Segphos complex has been developed. Both (Z)-α,β- and β,β-disubstituted substrates can be successfully hydrogenated to afford chiral boronates with excellent enantioselectivities, up to 98 % ee. Furthermore, the obtained chiral boronate esters, as important versatile synthetic intermediates are successfully transformed to the corresponding chiral alcohols, amines and other important derivatives with maintained enantioselectivities.
Stereoselective Synthesis of Trisubstituted Alkenylboron Reagents by Boron-Wittig Reaction of Ketones
Namirembe, Sheila,Gao, Chenpeng,Wexler, Ryan P.,Morken, James P.
supporting information, p. 4392 - 4394 (2019/06/14)
Application of the boron-Wittig reaction to ketone electrophiles provides a straightforward route to trisubstituted alkenylboronic esters. With either a pentamethyldiethylenetriamine or trimethyl-1,4,7-triazacyclononane additive, the olefination can occur
