1190-91-6

Basic information

• Product Name: 3-Buten-2-one, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)
• Synonyms: 3-Buten-2-one, 4-(dimethylamino)- (6CI,7CI,8CI,9CI);1-(Dimethylamino)-1-butene-3-one;2-(Dimethylamino)vinylmethyl ketone;4-(Dimethylamino)-3-buten-2-one;Methyl 2-(dimethylamino)vinyl ketone;Methyl - (diMethylaMino)vinyl ketone
• CAS NO: 1190-91-6
• Molecular Formula: C₆H₁₁NO
• Molecular Weight: 113.16
• Product Categories: ACETYLGROUP
• Mol File: 1190-91-6.mol
• Article Data: 17

Chemical Properties

• Boiling Point: 131-133 °C(Press: 20 Torr)
• Appearance: /
• Density: 0.9734 g/cm3
• Storage Temp.: 2-8°C
• PKA: 6.65±0.70(Predicted)
• CAS DataBase Reference: 3-Buten-2-one, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Buten-2-one, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)(1190-91-6)
• EPA Substance Registry System: 3-Buten-2-one, 4-(dimethylamino)- (6CI,7CI,8CI,9CI)(1190-91-6)

Safety Data

• Hazardous Substances Data: 1190-91-6(Hazardous Substances Data)

Usage

Description

3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI), also known as dimethylaminocrotonaldehyde, is an organic compound with the molecular formula C7H11NO. It belongs to the ketone and amine functional groups and is characterized by its pale yellow liquid appearance, pungent odor, and solubility in water and most organic solvents. 3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) is widely used in various industries due to its versatile properties and applications.

Uses

Used in Organic Synthesis:
3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) is used as a reagent in organic synthesis for the production of various pharmaceuticals and agrochemicals. Its unique chemical structure allows it to participate in a range of reactions, making it a valuable component in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) serves as a precursor for the development of various drugs. Its ability to form different chemical bonds and participate in multiple reactions contributes to the creation of new and effective medications.
Used in Agrochemical Industry:
3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) is also utilized as a precursor in the agrochemical industry for the synthesis of pesticides and other agricultural chemicals. Its role in the development of these products helps improve crop protection and yield.
Used in Food Industry:
In the food industry, 3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) is employed as a flavoring agent. Its unique aroma and taste profile contribute to the enhancement of various food products, providing consumers with a more enjoyable sensory experience.
Used in Cosmetic and Personal Care Industry:
3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) is used as a fragrance in the cosmetic and personal care industry. Its distinct scent is incorporated into various products such as perfumes, lotions, and creams, adding a pleasant aroma and enhancing the overall appeal of these products.
However, it is crucial to handle 3-Buten-2-one, 4-(dimethylamino)(6CI,7CI,8CI,9CI) with care, as it is known to be an irritant to the skin, eyes, and respiratory system. Proper safety measures should be taken during its use to minimize potential health risks.

Upstream product

• 763-12-2 2-methyl-3,5-hexadiyn-2-ol 
• 124-40-3 dimethyl amine 
• 56754-11-1 1-diethylamino-2,4-pentadiyne 
• 5815-08-7 tert-Butoxybis(dimethylamino)methane 
• 67-64-1 acetone 
• 460-12-8 Butadiyne 
• 23074-57-9 4-ethoxybut-3-en-2-one 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 506-59-2 N,N-dimethylammonium chloride 
• 5436-21-5 acetylacetaldehyde dimethyl acetal 
• 109-94-4 formic acid ethyl ester 
• 41125-09-1 3-oxo-butyraldehyde; sodium enolate 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 122-57-6 1-Phenylbut-1-en-3-one 
• 22428-91-7 2-methyl-3-oxobutanal 
• 25299-40-5 1,5-bis(dimethylamino)-1,4-pentadien-3-one 
• 13858-95-2 1-(3-phenylisoxazol-4-yl)ethan-1-one 
• 34310-05-9 1-[3-(2,4,6-trimethyl-phenyl)-isoxazol-4-yl]-ethanone 
• 88860-93-9 1-(1-p-methoxyphenyl-1H-1,2,3-triazol-4-yl)ethanone 
• 88860-91-7 1-[4-Acetyl-1-(4-bromo-phenyl)-1H-pyrazol-3-yl]-ethanone 
• 87005-15-0 α-bromoacetoacetaldehyde 
• 88860-92-8 1-phenyl-3-ethoxycarbonyl-4-acetylpyrazole 
• 2011-51-0 4-Methoxybenzol-<1-azo-2'>-acetoxyacetaldehyd 
• 2011-47-4 4-Nitro-benzol-(1-azo-2')-acetoacetaldehyd 
• 2011-46-3 Benzol-(1-azo-2')-acetoacetaldehyd 
• 2011-50-9 3-Nitrobenzol-(1-azo-2')-acetoacetaldehyd 
• 187749-72-0 N-(6-methyl-2-oxo-2H-pyran-3-yl)benzamide 

Relevant articles and documents

Reactions of enaminoketones with CH-acidic compounds (author's transl)

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An expedient synthesis of highly functionalized 1,3-dienes by employing cyclopropenes asC4units

An efficient method has been described to synthesize dicarbonyl functionalized 1,3-dienes by cleaving the CC bond of enaminones with cyclopropenes in the presence of a rhodium catalyst. The acetate-substituted cyclopropenes are judiciously chosen as standardC4units of 1,3-diene precursors. The reactions are believed to undergo a unique cutting and insertion process, involving a CC bond cleavage of the enaminone and insertion of a newC(sp2) source with the formation of two C-C single bonds. A broad range of substrates can be used to synthesize the corresponding 1,3-dienes under very mild reaction conditions, including low catalyst-loading, ambient temperature, and a neutral reaction solvent.

METHOD FOR PRODUCING NITROGEN-CONTAINING COMPOUND

Provided is an efficient and economical production method of a nitrogen-containing compound. A method for producing a compound represented by the formula R3C(O)CH═CHNR1R2, including reacting a compound represented by the following formula (4) with more than 6-fold moles of a compound represented by the formula NR1R2C(O)H to give a reaction mixture of the compound represented by the formula (4) and the compound represented by the formula NR1R2C(O)H, and reacting the reaction mixture with a compound represented by the formula R3C(O)CH3 by using a basic compound: wherein X is a halogen atom and R1, R2 and R3 are each independently an alkyl group having 1-6 carbon atoms.

Compound preparation method

The invention relates to a compound preparation method. Organic solvents and sodium methylate are added into a reaction vessel, carbon monoxide is led into the reaction vessel to perform reaction, acetone and organic solvent mixed solution is dropped after reaction to continue reaction to generate an intermediate sodium salt as shown in a formula I, the intermediate sodium salt reacts with dimethylamine to generate 4-N, N-dimethyl butene-3-ketone as shown in a formula II. Synthesis steps can be finished in one vessel, and the compound preparation method is low in cost and suitable for industrialization production.