1191237-48-5

Basic information

• Product Name: C₃₄H₃₃N₅O₄
• Synonyms: C₃₄H₃₃N₅O₄
• CAS NO: 1191237-48-5
• Molecular Weight: 575.667
• Mol File: 1191237-48-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₃₄H₃₃N₅O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₄H₃₃N₅O₄(1191237-48-5)
• EPA Substance Registry System: C₃₄H₃₃N₅O₄(1191237-48-5)

Safety Data

• Hazardous Substances Data: 1191237-48-5(Hazardous Substances Data)

Upstream product

• 7677-24-9 trimethylsilyl cyanide 
• 100-44-7 benzyl chloride 
• 1314972-33-2 (3R,4R,5R)-3,4-bis(benzyloxy)-5-(benzyloxymethyl)-3-methyl-tetrahydro-furan-2-ol 
• 1191237-41-8 C₂₈H₃₂O₅ 
• 917567-08-9 (3R,4R,5R)-3,4-bis(benzyloxy)-5-[(benzyloxy)methyl]-3-methyloxolan-2-one 
• 1191237-40-7 C₇H₁₄O₅ 

Downstream Products

• 1350736-07-0 C₁₃H₁₅N₅O₄ 
• 1191237-49-6 1′-cyano-2′-C-methyl-4-aza-7,9-dideazaadenosine 
• 1350735-57-7 (2S)-isopropyl 2-((((2R,3R,4R,5R)-5-(4-aminopyrrolo[1,2-f]-[1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate 
• 1350735-68-0 (2S)-isopropyl 2-((((2R,3R,4R,5R)-3-isobutyroxy-5-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-5-cyano-4-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate 
• 1350735-69-1 C₂₉H₃₇N₆O₉P 
• 1350735-70-4 [(Sp)-isopropyl 2-((S)-(((2R,3R,4R,5R)-3-isobutyroxy-5-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-5-cyano-4-hydroxy-4-methyltetrahydrofuran-2-yl)methoxy) (phenoxy)phosphorylamino)propanoate] 
• 1354823-59-8 (Sp)-isopropyl 2-((S)-(((2R,3R,4R,5R)-5-(4-aminopyrrolo[1,2-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxy-4-methyltetrahydrofuran-2-yl)methoxy)(phenoxy)phosphorylamino)propanoate 

Relevant articles and documents

METHODS FOR TREATING HCV

This invention relates to combinations of therapeutic molecules useful for treating hepatitis C virus infection. The present invention relates to methods, uses, dosing regimens, and compositions.

1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT

Provided are prodrugs of pyrrolo[l,2-f][l,2,4]triazin-7-yl nucleoside phosphates wherein the 1 '' position of the nucleoside sugar is substituted with CN. The compounds, compositions, and methods provided are useful for the treatment Hepatitis C infections.