1200405-67-9

Basic information

• Product Name: tert-butyl (S)-{1-[benzhydryl(methyl)amino]-3,3-dimethyl-1-oxobutan-2-yl}carbamate
• Synonyms: tert-butyl (S)-{1-[benzhydryl(methyl)amino]-3,3-dimethyl-1-oxobutan-2-yl}carbamate
• CAS NO: 1200405-67-9
• Molecular Weight: 410.557
• Mol File: 1200405-67-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: tert-butyl (S)-{1-[benzhydryl(methyl)amino]-3,3-dimethyl-1-oxobutan-2-yl}carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (S)-{1-[benzhydryl(methyl)amino]-3,3-dimethyl-1-oxobutan-2-yl}carbamate(1200405-67-9)
• EPA Substance Registry System: tert-butyl (S)-{1-[benzhydryl(methyl)amino]-3,3-dimethyl-1-oxobutan-2-yl}carbamate(1200405-67-9)

Safety Data

• Hazardous Substances Data: 1200405-67-9(Hazardous Substances Data)

Upstream product

• 62965-35-9 N-tert-butyloxycarbonyl-L-tert-leucine 
• 14683-47-7 N-(diphenylmethyl)methylamine 

Downstream Products

• 1421697-46-2 (S)-2-(3-((1S,2S)-2-aminocyclohexyl)thioureido)-N-benzhydryl-N,3,3-trimethylbutanamide 
• 1421697-48-4 (S)-2-(3-((1R,2R)-2-amino-1,2-diphenylethyl)thioureido)-N-benzhydryl-N,3,3-trimethylbutanamide 
• 1421697-50-8 (S)-2-(3-((1S,2S)-2-amino-1,2-diphenylethyl)thioureido)-N-benzhydryl-N,3,3-trimethylbutanamide 
• 1186602-39-0 (S)-N-benzhydryl-2-(3-cyclohexylthioureido)-N,3,3-trimethylbutanamide 
• 1186602-26-5 (S)-2-amino-N-benzhydryl-N,3,3-trimethylbutanamide 
• 1421697-44-0 (S)-N-benzhydryl-2-isothiocyanato-N,3,3-trimethylbutanamide 
• 1421052-39-2 (S)-2-(3-((1R,2R)-2-aminocyclohexyl)thioureido)-N-benzhydryl-N,3,3-trimethylbutanamide 
• 1186602-28-7 (S)-N-benzhydryl-2-(3-(3,5-bis(trifluoromethyl)phenyl)thioureido)-N,3,3-trimethyl butanamide 
• 959979-72-7 (S)-N-benzhydryl-N,3,3-trimethyl-2-(3-((1R,2R)-2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)cyclohexyl)thioureido)butanamide 

Relevant articles and documents

Bifunctional Squaramide Organocatalysts for the Asymmetric Addition of Formaldehyde tert-Butylhydrazone to Simple Aldehydes

The nucleophilic addition of formaldehyde tert-butylhydrazone to simple aldehydes (a formal hetero-carbonyl–ene reaction) can be performed with good reactivity and excellent enantioselectivity by virtue of the dual hydrogen-bonding activation exerted by amide–squaramide organocatalysts. The resulting hydroxydiazenes (azo alcohols) were isolated in high yields as enantiomerically enriched azoxy compounds after a regioselective azo-to-azoxy transformation. Subsequent derivatization provides an entry to relevant amino alcohols, oxazolidinones, and derivatives thereof.

COMPOUNDS AND RELATED METHODS OF USE

Described herein are compounds of formula (I), related compositions, and their use, for example in the formation of α-amino acids or a precursor thereof such as an α-aminonitrile.