120122-47-6

Basic information

• Product Name: 1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE
• Synonyms: 2,2,2-TRICHLORO-1-(1-METHYL-4-NITRO-1H-PYRROL-2-YL)-ETHANONE;1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE;N-METHYL-4-NITRO-2-TRICHLOROACETYLPYRROLE;2-Trichloro-1-(1-methyl-4-nitro-1H-pyrrol-2-yl)ethanone;2,2,2-Trichloro-1-(1-methyl-4-nitro-1H-pyrrol-2-yl;1-methyl-4-nitro-2-trichloroacetyl pyrrole;2-(Trichloroacetyl)-1-methyl-4-nitropyrrole;4-Nitro-2-(trichloroacetyl)-N-methylpyrrole
• CAS NO: 120122-47-6
• Molecular Formula: C₇H₅Cl₃N₂O₃
• Molecular Weight: 271.49
• Mol File: 120122-47-6.mol

Chemical Properties

• Melting Point: 132-135°C
• Boiling Point: 319.1 °C at 760 mmHg
• Flash Point: 146.8 °C
• Appearance: /
• Density: 1.66
• Vapor Pressure: 0.000345mmHg at 25°C
• Refractive Index: 1.616
• Storage Temp.: -15°C
• PKA: -15.07±0.70(Predicted)
• CAS DataBase Reference: 1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE(120122-47-6)
• EPA Substance Registry System: 1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE(120122-47-6)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 120122-47-6(Hazardous Substances Data)

Usage

Description

1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE is a chemical compound characterized by its unique molecular structure, which features a pyrrole ring with a methyl group at the 1st position, a nitro group at the 4th position, and a trichloroacetyl group at the 2nd position. 1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE is known for its potential applications in various fields due to its chemical properties.

Uses

1. Used in Chemical Research:
1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE is used as a chemical intermediate for the synthesis of various complex organic molecules. Its unique structure allows it to be a valuable building block in the development of new compounds with specific properties and applications.
2. Used in Pharmaceutical Industry:
1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE is used as a key component in the development of novel drugs. Its chemical properties make it a promising candidate for the creation of new therapeutic agents, particularly in the areas of cancer treatment and other diseases.
3. Used in DNA-binding Studies:
1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE is used as a starting material to develop DNA-binding TEMPO derivatives. These derivatives are essential for evaluating nuclear oxidative stress, which is a critical factor in understanding the mechanisms of various diseases and the development of potential treatments.
4. Used in Material Science:
1-METHYL-4-NITRO-2-(TRICHLOROACETYL)-1H-PYRROLE can be utilized in the development of new materials with specific properties, such as improved stability, reactivity, or selectivity. Its unique structure and chemical properties make it a valuable component in the design and synthesis of advanced materials for various applications.

InChI:InChI=1/C7H5Cl3N2O3/c1-11-3-4(12(14)15)2-5(11)6(13)7(8,9)10/h2-3H,1H3