120285-30-5Relevant articles and documents
Synthesis and Reactions of Isoquinoline Derivatives II. Synthesis of 3-Chloroisoquinoline-4-aldehydes
Bartmann, W.,Konz, E.,Rueger, W.
, p. 680 - 683 (2007/10/02)
1-Aryl-substituted 1,4-dihydro-3(2H)isoquinolinones 1 are easily converted to 1-aryl-3-chloroisoquinoline-4-aldehydes 3 by a two-step procedure involving a Vilsmeier-Haack reaction followed by subsequent oxidation with potassium permanganate under acidic