1215-07-2

Basic information

• Product Name: α-Nitrostilbene
• Synonyms: ALPHA-NITROSTILBENE;(1-Nitroethene-1,2-diyl)dibenzene
• CAS NO: 1215-07-2
• Molecular Formula: C₁₄H₁₁NO₂
• Molecular Weight: 225.246
• Product Categories: Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1215-07-2.mol
• Article Data: 27

Chemical Properties

• Appearance: /
• CAS DataBase Reference: α-Nitrostilbene(CAS DataBase Reference)
• NIST Chemistry Reference: α-Nitrostilbene(1215-07-2)
• EPA Substance Registry System: α-Nitrostilbene(1215-07-2)

Safety Data

• Hazardous Substances Data: 1215-07-2(Hazardous Substances Data)

Usage

Description

α-Nitrostilbene is an organic compound that serves as an analog of 4-Nitrostilbene. It is characterized by its chemical structure and properties, which have been the subject of recent research due to its potential applications in various fields.

Uses

Used in Pharmaceutical Industry:
α-Nitrostilbene is used as an inhibitor for arginine methyltransferase-1 (PRMT1) due to its ability to show inhibitory effects towards this enzyme. This application is significant because PRMT1 plays a crucial role in various cellular processes, and its dysregulation has been linked to several diseases, making α-Nitrostilbene a promising candidate for therapeutic intervention in conditions related to PRMT1 overactivity or misregulation.

Upstream product

• 110-86-1 pyridine 
• 64-17-5 ethanol 
• 622-42-4 1-nitro-1-phenylmethane 
• 100-52-7 benzaldehyde 
• 67-64-1 acetone 
• 6852-55-7 N-benzylidenepropylamine 
• 13286-95-8 meso-1,2-dinitro-1,2-diphenylethane 
• 13440-25-0 (+/-)-1,2-dinitro-1,2-diphenylethane 
• 28531-58-0 (2-oxo-2-phenylethyl)mercury chloride 
• 12413-18-2 phenylnitromethane carbanion 
• 116467-25-5 C₁₆H₁₆NO₂S^(1-) 
• 116467-21-1 C₁₆H₁₆NO₃S^(1-) 
• 116467-26-6 C₁₈H₁₈NO₄S^(1-) 
• 154077-82-4 C₁₄H₁₂NO₃^(1-) 

Downstream Products

• 876477-04-2 (α'-bromo-α'-nitro-bibenzyl-α-yl)-methyl ether 
• 22020-72-0 triphenylizoxazole 
• 854831-27-9 (α'-nitro-bibenzyl-α-yl)-malonic acid diethyl ester 
• 26306-06-9 (E)-benzyl phenyl ketoxime 
• 5452-30-2 (+/-)-3,4r,5t-triphenyl-4,5-dihydro-isoxazole-2-oxide 
• 55109-46-1 1,3-dinitro-1,2-diphenyl-propane 
• 15341-31-8 ((Z)-(1-nitroethene-1,2-diyl)dibenzene) 
• 100870-19-7 DL-threo-2-Nitro-1-amino-1,2-diphenylethan 
• 101947-77-7 complex of piperidine with cis-α-nitrostilbene 
• 116467-25-5 C₁₆H₁₆NO₂S^(1-) 
• 124645-68-7 (2R,3R)-1-Oxy-3,4-diphenyl-2-((Z)-propenyl)-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 124645-68-7 (2R,3R)-1-Oxy-3,4-diphenyl-2-((E)-propenyl)-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 124645-67-6 (2R,3R)-1-Oxy-3,4-diphenyl-2-vinyl-2,3-dihydro-azete-2-carboxylic acid diethylamide 
• 116467-27-7 2-(2-Nitro-1,2-diphenyl-ethylsulfanyl)-ethanol 

Relevant articles and documents

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Synthesis of Benzo[4,5]imidazo[2,1-b]thiazole by Copper(II)-Catalyzed Thioamination of Nitroalkene with 1H-Benzo[d]imidazole-2-thiol

A Copper(II)-catalyzed thioamination of β-nitroalkene with 1H-benzo[d]imidazole-2-thiol has been developed for the synthesis of benzo[4,5]imidazo[2,1-b]thiazole derivatives. A variety of N-fused benzoimidazothiazole derivatives are obtained in high yields through successive C?N and C?S bond formations. This protocol is also applicable to β-substituted β-nitroalkenes to afford 2,3-disubstituted benzoimidazothiazoles. (Figure presented.).

PREPARATION OF ALDEHYDES AND KETONES FROM ALKENES USING POLYOXOMETALATE CATALYSTS AND NITROGEN OXIDES

The present invention relates to a process for preparing aldehydes and ketones by carbon-carbon bond cleavage of alkenes, wherein the process is catalysed by first row transition metal nitro coordinated polyoxometalate catalyst. The catalyst can be prepared by pre-treatment of aqua coordinated polyoxometalates with NO2, or they are formed in situ when the reactions are carried in nitroalkanes under aerobic conditions, or they are formed in situ from nitrosyl (NO) compounds in the presence of O2.