122-06-5

Basic information

• Product Name: stilbamidine
• Synonyms: 4,4-diamidinostilbene; 4,4'-ethene-1,2-diyldibenzenecarboximidamide; 4,4'-(E)-ethene-1,2-diyldibenzenecarboximidamide
• CAS NO: 122-06-5
• Molecular Formula: C₁₀H₁₂O₂
• Molecular Weight: 264.325
• EINECS: 204-519-5
• Mol File: 122-06-5.mol
• Article Data: 174

Chemical Properties

• Boiling Point: 456.4°C at 760 mmHg
• Flash Point: 229.8°C
• Density: 1.19g/cm³
• Vapor Pressure: 1.62E-08mmHg at 25°C
• Refractive Index: 1.634
• CAS DataBase Reference: stilbamidine(CAS DataBase Reference)
• NIST Chemistry Reference: stilbamidine(122-06-5)
• EPA Substance Registry System: stilbamidine(122-06-5)

Safety Data

• Hazardous Substances Data: 122-06-5(Hazardous Substances Data)

Usage

General Description

Stilbamidine is a synthetic compound and an organic chemical that is used as an antiprotozoal medication, particularly in the treatment of leishmaniasis, a parasitic infection caused by the Leishmania species. It works by inhibiting the growth and replication of the parasites, ultimately leading to their death. Stilbamidine is typically administered through injection into the muscles or veins, and its use is limited to treatment of severe cases of leishmaniasis that do not respond to other available medications. It is known to have potential side effects such as kidney toxicity, so its use is closely monitored by healthcare professionals. Stilbamidine is not widely used and is not typically available in all regions, but it remains an important option for the treatment of leishmaniasis in certain circumstances.

Upstream product

• 3424-93-9 4-methoxyphenylacetamide 
• 925-90-6 ethylmagnesium bromide 
• 7448-86-4 1-(4-methoxyphenyl)prop-2-en-1-one 
• 7465-86-3 4-methoxy-N,N-diethylbenzamide 
• 1201-60-1 1-(1,2-dibromopropyl)-4-methoxybenzene 
• 127193-12-8 2-bromo-1-methoxy-1-(4-methoxyphenyl)-propane 
• 124-41-4 sodium methylate 
• 857591-12-9 1-(1-ethoxy-2-bromo-propyl)-4-methoxy-benzene 
• 141-52-6 sodium ethanolate 
• 79-03-8 propionyl chloride 
• 100-66-3 methoxybenzene 
• 2125-49-7 3-dimethylamino-1-(4-methoxy-phenyl)-propan-1-one; hydrochloride 
• 802294-64-0 propionic acid 
• 123-62-6 propionic acid anhydride 

Downstream Products

• 133005-88-6 cis-stilbene-4,4’-dicarboxylic acid 

Relevant articles and documents

Copper-Catalyzed Methoxylation of Aryl Bromides with 9-BBN-OMe

A Cu-catalyzed cross-coupling reaction between aryl bromides and 9-BBN-OMe to provide aryl methyl ethers under mild conditions is reported. The oxalamide ligand BHMPO plays a key role in the transformation. Various functional groups on bromobenzenes are well tolerated, providing the desired anisole products in moderate to high yields.

Method for preparing ketone compound from olefin

The invention belongs to the technical field of organic chemical synthesis, and discloses a method for preparing a ketone compound from olefin by using an iron catalyst. According to the invention, the ligand and the iron salt form an iron catalyst in the on-site reaction, the raw materials in the formula are easy to obtain, and the synthesis is simple. By using the catalyst, olefin can be efficiently converted into ketone compounds, and compared with a palladium catalyst, the price is very low, and the catalyst is suitable for industrial application.